This proposal continues a multimethod longitudinal appraisal of infant temperament and potential correlates, such as family environment and parent personality, using a sample of twins studied from birth through 30 months of age. Infant twins offer a powerful resource for detecting genetically based similarities and differences for both level and stability of temperament. Twins also provide an opportunity to detect specific contributions of family environment to both level and stability of temperament. The principal goals of the current proposal are: 1) Finish recruiting newborn twin pairs who will be repeatedly assessed through 30 months of age using the instruments described below; 2) Finish assessment of twin pairs who are currently being assessed; 3) Rescore previously obtained videotapes of twin performance during the laboratory procedures used to assess temperament; and 4) Provide further evidence on the validity of a nurses rating survey of neonatal temperament. The ultimate goal of the project is to analyze the data collected for the full sample of 280 twin pairs, using multitrait, multimethod genetic analysis. Questions to be answered by this analysis include the origins, degree and sources of intraage variability and interage stability of temperament, as well as the interrelation of genetic and environmental factors in the development of temperament. Temperament measures include assessment of neonatal irritability, reactivity and developmental status; direct observation of temperament related behaviors during standardized testing in a structured laboratory situation for seven assessments from 3 through 30 months; parent ratings on standard temperament questionnaires including the Carey Scales and Rothbart Infant Behavior Questionnaire, as well as Infant Behavior ratings obtained during mental testing. Environmental measures include a newly developed CHAOS scale, the FES scales, as well as direct observations at 7 and 30 months using codes derived from current environmental assessment techniques. Parent personality is assessed using several parent report measures.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
2R01HD022637-08
Application #
2198618
Study Section
Special Emphasis Panel (ZRG1-HUD-3 (02))
Project Start
1987-02-01
Project End
1997-01-31
Budget Start
1994-02-01
Budget End
1995-01-31
Support Year
8
Fiscal Year
1994
Total Cost
Indirect Cost
Name
University of Louisville
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
Louisville
State
KY
Country
United States
Zip Code
40292
Riese, Marilyn L; Swift, Hallie M; Barnes, Steffany L (2003) Newborn twin outcome predicted by maternal variables: differentiation by term and sex. Twin Res 6:12-8
Mastropaolo, W; Matheny Jr Jr, A; Lang, C A (2001) Plasma cholesterol concentrations in twin children: estimates of genetic and environmental influences. Clin Chem 47:771
Riese, M L (2001) Discordant and nondiscordant twins: comparative multimethod risk assessment in the neonatal period. J Dev Behav Pediatr 22:102-12
Andrews, K; Francis, D J; Riese, M L (2000) Prenatal cocaine exposure and prematurity: neurodevelopmental growth. J Dev Behav Pediatr 21:262-70
Finkel, D; Matheny Jr, A P (2000) Genetic and environmental influences on a measure of infant attachment security. Twin Res 3:242-50
Riese, M L (1999) Effects of chorion type on neonatal temperament differences in monozygotic twin pairs. Behav Genet 29:87-94
Riese, M L (1998) Predicting infant temperament from neonatal reactivity for AGA/SGA twin pairs. Twin Res 1:65-70
Finkel, D; Wille, D E; Matheny Jr, A P (1998) Preliminary results from a twin study of infant--caregiver attachment. Behav Genet 28:1-8
Phillips, K; Matheny Jr, A P (1997) Evidence for genetic influence on both cross-situation and situation-specific components of behavior. J Pers Soc Psychol 73:129-38
Bito, L Z; Matheny, A; Cruickshanks, K J et al. (1997) Eye color changes past early childhood. The Louisville Twin Study. Arch Ophthalmol 115:659-63

Showing the most recent 10 out of 24 publications