Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD026402-07
Application #
2199927
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Project Start
1990-01-01
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Virginia
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
001910777
City
Charlottesville
State
VA
Country
United States
Zip Code
22904
DeSimone, Douglas W; Horwitz, A Rick (2014) Cell Biology. Many modes of motility. Science 345:1002-3
Rozario, Tania; Mead, Paul E; DeSimone, Douglas W (2014) Diverse functions of kindlin/fermitin proteins during embryonic development in Xenopus laevis. Mech Dev 133:203-17
Bjerke, Maureen A; Dzamba, Bette J; Wang, Chong et al. (2014) FAK is required for tension-dependent organization of collective cell movements in Xenopus mesendoderm. Dev Biol 394:340-56
Weber, Gregory F; Bjerke, Maureen A; DeSimone, Douglas W (2012) A mechanoresponsive cadherin-keratin complex directs polarized protrusive behavior and collective cell migration. Dev Cell 22:104-15
Wei, Shuo; Xu, Guofeng; Bridges, Lance C et al. (2012) Roles of ADAM13-regulated Wnt activity in early Xenopus eye development. Dev Biol 363:147-54
Schwarzbauer, Jean E; DeSimone, Douglas W (2011) Fibronectins, their fibrillogenesis, and in vivo functions. Cold Spring Harb Perspect Biol 3:
Weber, Gregory F; Bjerke, Maureen A; DeSimone, Douglas W (2011) Integrins and cadherins join forces to form adhesive networks. J Cell Sci 124:1183-93
Wei, Shuo; Xu, Guofeng; Bridges, Lance C et al. (2010) ADAM13 induces cranial neural crest by cleaving class B Ephrins and regulating Wnt signaling. Dev Cell 19:345-52
Wei, Shuo; Whittaker, Charles A; Xu, Guofeng et al. (2010) Conservation and divergence of ADAM family proteins in the Xenopus genome. BMC Evol Biol 10:211
Rozario, Tania; DeSimone, Douglas W (2010) The extracellular matrix in development and morphogenesis: a dynamic view. Dev Biol 341:126-40

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