Funding Agency

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
2R01HD028341-04
Application #
2201016
Study Section
Neurology B Subcommittee 2 (NEUB)
Project Start
1992-08-01
Project End
1999-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Massachusetts Institute of Technology
Department
Other Basic Sciences
Type
Other Domestic Higher Education
DUNS #
City
Cambridge
State
MA
Country
United States
Zip Code
02139

  Publications

Crittenden, Jill R; Lacey, Carolyn J; Weng, Feng-Ju et al. (2017) Striatal Cholinergic Interneurons Modulate Spike-Timing in Striosomes and Matrix by an Amphetamine-Sensitive Mechanism. Front Neuroanat 11:20
Kalueff, Allan V; Stewart, Adam Michael; Song, Cai et al. (2016) Neurobiology of rodent self-grooming and its value for translational neuroscience. Nat Rev Neurosci 17:45-59
Burguière, Eric; Monteiro, Patrícia; Feng, Guoping et al. (2013) Optogenetic stimulation of lateral orbitofronto-striatal pathway suppresses compulsive behaviors. Science 340:1243-6
Crittenden, Jill R; Dunn, Denise E; Merali, Farhan I et al. (2010) CalDAG-GEFI down-regulation in the striatum as a neuroprotective change in Huntington's disease. Hum Mol Genet 19:1756-65
Crittenden, Jill R; Cantuti-Castelvetri, Ippolita; Saka, Esen et al. (2009) Dysregulation of CalDAG-GEFI and CalDAG-GEFII predicts the severity of motor side-effects induced by anti-parkinsonian therapy. Proc Natl Acad Sci U S A 106:2892-6
Pasvolsky, Ronit; Feigelson, Sara W; Kilic, Sara Sebnem et al. (2007) A LAD-III syndrome is associated with defective expression of the Rap-1 activator CalDAG-GEFI in lymphocytes, neutrophils, and platelets. J Exp Med 204:1571-82
Bergmeier, Wolfgang; Goerge, Tobias; Wang, Hong-Wei et al. (2007) Mice lacking the signaling molecule CalDAG-GEFI represent a model for leukocyte adhesion deficiency type III. J Clin Invest 117:1699-707
Bernardi, Bruno; Guidetti, Gianni F; Campus, Francesca et al. (2006) The small GTPase Rap1b regulates the cross talk between platelet integrin alpha2beta1 and integrin alphaIIbbeta3. Blood 107:2728-35
Crittenden, Jill R; Bergmeier, Wolfgang; Zhang, Yanyu et al. (2004) CalDAG-GEFI integrates signaling for platelet aggregation and thrombus formation. Nat Med 10:982-6
Toki, S; Kawasaki, H; Tashiro, N et al. (2001) Guanine nucleotide exchange factors CalDAG-GEFI and CalDAG-GEFII are colocalized in striatal projection neurons. J Comp Neurol 437:398-407

Showing the most recent 10 out of 19 publications