Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL024526-18
Application #
2215767
Study Section
Physical Biochemistry Study Section (PB)
Project Start
1979-07-01
Project End
2000-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
18
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Oregon
Department
Type
Organized Research Units
DUNS #
948117312
City
Eugene
State
OR
Country
United States
Zip Code
97403
Hanson, George T; Aggeler, Robert; Oglesbee, Devin et al. (2004) Investigating mitochondrial redox potential with redox-sensitive green fluorescent protein indicators. J Biol Chem 279:13044-53
Schulenberg, Birte; Aggeler, Robert; Beechem, Joseph M et al. (2003) Analysis of steady-state protein phosphorylation in mitochondria using a novel fluorescent phosphosensor dye. J Biol Chem 278:27251-5
Capaldi, Roderick A; Aggeler, Robert (2002) Mechanism of the F(1)F(0)-type ATP synthase, a biological rotary motor. Trends Biochem Sci 27:154-60
Aggeler, Robert; Coons, Juliana; Taylor, Steven W et al. (2002) A functionally active human F1F0 ATPase can be purified by immunocapture from heart tissue and fibroblast cell lines. Subunit structure and activity studies. J Biol Chem 277:33906-12
Tsunoda, S P; Aggeler, R; Yoshida, M et al. (2001) Rotation of the c subunit oligomer in fully functional F1Fo ATP synthase. Proc Natl Acad Sci U S A 98:898-902
Triepels, R H; Hanson, B J; van den Heuvel, L P et al. (2001) Human complex I defects can be resolved by monoclonal antibody analysis into distinct subunit assembly patterns. J Biol Chem 276:8892-7
Tsunoda, S P; Rodgers, A J; Aggeler, R et al. (2001) Large conformational changes of the epsilon subunit in the bacterial F1F0 ATP synthase provide a ratchet action to regulate this rotary motor enzyme. Proc Natl Acad Sci U S A 98:6560-4
Hausrath, A C; Capaldi, R A; Matthews, B W (2001) The conformation of the epsilon- and gamma-subunits within the Escherichia coli F(1) ATPase. J Biol Chem 276:47227-32
Hanson, B J; Carrozzo, R; Piemonte, F et al. (2001) Cytochrome c oxidase-deficient patients have distinct subunit assembly profiles. J Biol Chem 276:16296-301
Capaldi, R A; Schulenberg, B; Murray, J et al. (2000) Cross-linking and electron microscopy studies of the structure and functioning of the Escherichia coli ATP synthase. J Exp Biol 203:29-33

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