Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
3R01HL028573-13S1
Application #
937484
Study Section
Biochemistry Study Section (BIO)
Project Start
1982-09-01
Project End
1996-03-31
Budget Start
1995-04-01
Budget End
1996-03-31
Support Year
13
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Cincinnati
Department
Genetics
Type
Schools of Medicine
DUNS #
City
Cincinnati
State
OH
Country
United States
Zip Code
45221
Radzyukevich, Tatiana L; Neumann, Jonathon C; Rindler, Tara N et al. (2013) Tissue-specific role of the Na,K-ATPase ?2 isozyme in skeletal muscle. J Biol Chem 288:1226-37
Rindler, Tara N; Lasko, Valerie M; Nieman, Michelle L et al. (2013) Knockout of the Na,K-ATPase ?2-isoform in cardiac myocytes delays pressure overload-induced cardiac dysfunction. Am J Physiol Heart Circ Physiol 304:H1147-58
Lorenz, John N; Oshiro, Naomi; Loreaux, Elizabeth L et al. (2012) DOCA-salt hypertension does not require the ouabain-sensitive binding site of the ?2 Na,K-ATPase. Am J Hypertens 25:421-9
Despa, Sanda; Lingrel, Jerry B; Bers, Donald M (2012) Na(+)/K)+)-ATPase ?2-isoform preferentially modulates Ca2(+) transients and sarcoplasmic reticulum Ca2(+) release in cardiac myocytes. Cardiovasc Res 95:480-6
Rindler, Tara N; Dostanic, Iva; Lasko, Valerie M et al. (2011) Knockout of the Na,K-ATPase ýýýýý-isoform in the cardiovascular system does not alter basal blood pressure but prevents ACTH-induced hypertension. Am J Physiol Heart Circ Physiol 301:H1396-404
Schaefer, Tori L; Lingrel, Jerry B; Moseley, Amy E et al. (2011) Targeted mutations in the Na,K-ATPase ? 2 isoform confer ouabain resistance and result in abnormal behavior in mice. Synapse 65:520-31
Lorenz, John N; Lasko, Valerie M; Nieman, Michelle L et al. (2011) Renovascular hypertension using a modified two-kidney, one-clip approach in mice is not dependent on the *1 or *2 Na-K-ATPase ouabain-binding site. Am J Physiol Renal Physiol 301:F615-21
Wansapura, Arshani N; Lasko, Valerie M; Lingrel, Jerry B et al. (2011) Mice expressing ouabain-sensitive ?1-Na,K-ATPase have increased susceptibility to pressure overload-induced cardiac hypertrophy. Am J Physiol Heart Circ Physiol 300:H347-55
DeAndrade, Mark P; Yokoi, Fumiaki; van Groen, Thomas et al. (2011) Characterization of Atp1a3 mutant mice as a model of rapid-onset dystonia with parkinsonism. Behav Brain Res 216:659-65
Lingrel, Jerry B (2010) The physiological significance of the cardiotonic steroid/ouabain-binding site of the Na,K-ATPase. Annu Rev Physiol 72:395-412

Showing the most recent 10 out of 86 publications