Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL029847-14
Application #
2216528
Study Section
Experimental Cardiovascular Sciences Study Section (ECS)
Project Start
1983-02-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
14
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Northeastern University
Department
Other Health Professions
Type
Schools of Pharmacy
DUNS #
039318308
City
Boston
State
MA
Country
United States
Zip Code
02115
Mori, Takefumi; Dickhout, Jeffrey G; Cowley Jr, Allen W (2002) Vasopressin increases intracellular NO concentration via Ca(2+) signaling in inner medullary collecting duct. Hypertension 39:465-9
Tian, W N; Miller, D D; Deth, R C (2000) Bidirectional allosteric effects of agonists and GTP at alpha(2A/D)-adrenoceptors. J Pharmacol Exp Ther 292:664-71
Jinsi-Parimoo, A; Deth, R C (2000) Protein kinase C-dependent coupling of alpha(2A/D)-adrenergic receptors to phospholipase D. Pharmacology 60:19-26
Jinsi-Parimoo, A; Deth, R C (1997) Reconstitution of alpha2D-adrenergic receptor coupling to phospholipase D in a PC12 cell lysate. J Biol Chem 272:14556-61
Tian, W N; Duzic, E; Deth, R C (1996) Evaluation of agonist efficacy and receptor reserve for alpha 2D-adrenergic receptor regulated G protein activation in PC12 cell membranes. Pharmacology 52:252-62
Jinsi, A; Paradise, J; Deth, R C (1996) A tyrosine kinase regulates alpha-adrenoceptor-stimulated contraction and phospholipase D activation in the rat aorta. Eur J Pharmacol 302:183-90
Waen-Safranchik, V I; Deth, R C (1994) Effects of wortmannin on alpha-1/alpha-2 adrenergic receptor-mediated contractile responses in rabbit vascular tissues. Pharmacology 48:349-59
Shi, A G; Deth, R C (1994) Precoupling of alpha-2B adrenergic receptors and G-proteins in transfected PC-12 cell membranes: influence of pertussis toxin and a lysine-directed cross-linker. J Pharmacol Exp Ther 271:1520-7
Tian, W N; Duzic, E; Lanier, S M et al. (1994) Determinants of alpha 2-adrenergic receptor activation of G proteins: evidence for a precoupled receptor/G protein state. Mol Pharmacol 45:524-31
Jagadeesh, G; Deth, R C (1992) Phorbol ester and staurosporine modulation of antagonist and agonist binding to alpha-2 adrenergic receptors: differential influence on Na+ versus guanylylnucleotide regulation. J Pharmacol Exp Ther 262:775-83

Showing the most recent 10 out of 24 publications