Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
2R01HL032154-04
Application #
3343429
Study Section
Respiratory and Applied Physiology Study Section (RAP)
Project Start
1984-06-01
Project End
1987-08-31
Budget Start
1987-06-01
Budget End
1987-08-31
Support Year
4
Fiscal Year
1987
Total Cost
Indirect Cost
Name
Yale University
Department
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Stitt, Molly S; Wasserloos, K J; Tang, X et al. (2006) Nitric oxide-induced nuclear translocation of the metal responsive transcription factor, MTF-1 is mediated by zinc release from metallothionein. Vascul Pharmacol 44:149-55
Wilson, Annette; He, Fengtian; Li, Jiang et al. (2005) Targeted delivery of therapeutic oligonucleotides to pulmonary circulation. Adv Genet 54:21-41
Wilson, Annette; Zhou, Wen; Champion, Hunter C et al. (2005) Targeted delivery of oligodeoxynucleotides to mouse lung endothelial cells in vitro and in vivo. Mol Ther 12:510-8
Li, Jiang; Ma, Zheng; Tang, Zhi-Lue et al. (2004) CpG DNA-mediated immune response in pulmonary endothelial cells. Am J Physiol Lung Cell Mol Physiol 287:L552-8
Ma, Zheng; Li, Jiang; Yang, Lijuan et al. (2004) Inhibition of LPS- and CpG DNA-induced TNF-alpha response by oxidized phospholipids. Am J Physiol Lung Cell Mol Physiol 286:L808-16
St Croix, Claudette M; Stitt, Molly S; Leelavanichkul, Karanee et al. (2004) Nitric oxide-induced modification of protein thiolate clusters as determined by spectral fluorescence resonance energy transfer in live endothelial cells. Free Radic Biol Med 37:785-92
Collins, Joy L; Vodovotz, Yoram; Hierholzer, Christian et al. (2003) Characterization of the expression of inducible nitric oxide synthase in rat and human liver during hemorrhagic shock. Shock 19:117-22
Zhang, J; Wilson, A; Alber, S et al. (2003) Prolonged gene expression in mouse lung endothelial cells following transfection with Epstein-Barr virus-based episomal plasmid. Gene Ther 10:822-6
Tang, Zi-Lue; Wasserloos, Karla J; Liu, Xianghong et al. (2002) Nitric oxide decreases the sensitivity of pulmonary endothelial cells to LPS-induced apoptosis in a zinc-dependent fashion. Mol Cell Biochem 234-235:211-7
Wilson, Annette; Pitt, Bruce; Li, Song (2002) Complex roles of CpG in liposomal delivery of DNA and oligonucleotides. Biosci Rep 22:309-22

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