Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
2R01HL033333-09A3
Application #
2217236
Study Section
Physiology Study Section (PHY)
Project Start
1985-07-01
Project End
2000-06-30
Budget Start
1996-07-18
Budget End
1997-06-30
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Rochester
Department
Pharmacology
Type
Schools of Dentistry
DUNS #
208469486
City
Rochester
State
NY
Country
United States
Zip Code
14627

  Publications

O-Uchi, Jin; Jhun, Bong Sook; Xu, Shangcheng et al. (2014) Adrenergic signaling regulates mitochondrial Ca2+ uptake through Pyk2-dependent tyrosine phosphorylation of the mitochondrial Ca2+ uniporter. Antioxid Redox Signal 21:863-79
O-Uchi, Jin; Ryu, Shin-Young; Jhun, Bong Sook et al. (2014) Mitochondrial ion channels/transporters as sensors and regulators of cellular redox signaling. Antioxid Redox Signal 21:987-1006
Jakob, Regina; Beutner, Gisela; Sharma, Virendra K et al. (2014) Molecular and functional identification of a mitochondrial ryanodine receptor in neurons. Neurosci Lett 575:7-12
Sokolova, Niina; Pan, Shi; Provazza, Sarah et al. (2013) ADP protects cardiac mitochondria under severe oxidative stress. PLoS One 8:e83214
O-Uchi, Jin; Jhun, Bong Sook; Hurst, Stephen et al. (2013) Overexpression of ryanodine receptor type 1 enhances mitochondrial fragmentation and Ca2+-induced ATP production in cardiac H9c2 myoblasts. Am J Physiol Heart Circ Physiol 305:H1736-51
O-Uchi, Jin; Pan, Shi; Sheu, Shey-Shing (2012) Perspectives on: SGP symposium on mitochondrial physiology and medicine: molecular identities of mitochondrial Ca2+ influx mechanism: updated passwords for accessing mitochondrial Ca2+-linked health and disease. J Gen Physiol 139:435-43
Pan, Shi; Ryu, Shin-Young; Sheu, Shey-Shing (2011) Distinctive characteristics and functions of multiple mitochondrial Ca2+ influx mechanisms. Sci China Life Sci 54:763-9
Ryu, Shin-Young; Beutner, Gisela; Kinnally, Kathleen W et al. (2011) Single channel characterization of the mitochondrial ryanodine receptor in heart mitoplasts. J Biol Chem 286:21324-9
Hom, Jennifer R; Quintanilla, Rodrigo A; Hoffman, David L et al. (2011) The permeability transition pore controls cardiac mitochondrial maturation and myocyte differentiation. Dev Cell 21:469-78
Wei, Lan; Salahura, Gheorghe; Boncompagni, Simona et al. (2011) Mitochondrial superoxide flashes: metabolic biomarkers of skeletal muscle activity and disease. FASEB J 25:3068-78

Showing the most recent 10 out of 57 publications