Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
2R01HL035549-11
Application #
2217841
Study Section
Special Emphasis Panel (ZRG7-SAT (M1))
Project Start
1985-12-01
Project End
2000-05-30
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Pennsylvania State University
Department
Engineering (All Types)
Type
Schools of Engineering
DUNS #
City
University Park
State
PA
Country
United States
Zip Code
16802

  Publications

Qazi, Henry; Palomino, Rocio; Shi, Zhong-Dong et al. (2013) Cancer cell glycocalyx mediates mechanotransduction and flow-regulated invasion. Integr Biol (Camb) 5:1334-43
Qazi, Henry; Shi, Zhong-Dong; Tarbell, John M (2011) Fluid shear stress regulates the invasive potential of glioma cells via modulation of migratory activity and matrix metalloproteinase expression. PLoS One 6:e20348
Shi, Zhong-Dong; Ji, Xin-Ying; Berardi, Danielle E et al. (2010) Interstitial flow induces MMP-1 expression and vascular SMC migration in collagen I gels via an ERK1/2-dependent and c-Jun-mediated mechanism. Am J Physiol Heart Circ Physiol 298:H127-35
Berardi, Danielle E; Tarbell, John M (2009) Stretch and Shear Interactions Affect Intercellular Junction Protein Expression and Turnover in Endothelial Cells. Cell Mol Bioeng 2:320-331
Shi, Zhong-Dong; Ji, Xin-Ying; Qazi, Henry et al. (2009) Interstitial flow promotes vascular fibroblast, myofibroblast, and smooth muscle cell motility in 3-D collagen I via upregulation of MMP-1. Am J Physiol Heart Circ Physiol 297:H1225-34
Garanich, Jeffrey S; Mathura, Rishi A; Shi, Zhong-Dong et al. (2007) Effects of fluid shear stress on adventitial fibroblast migration: implications for flow-mediated mechanisms of arterialization and intimal hyperplasia. Am J Physiol Heart Circ Physiol 292:H3128-35
Pahakis, Manolis Y; Kosky, Jason R; Dull, Randal O et al. (2007) The role of endothelial glycocalyx components in mechanotransduction of fluid shear stress. Biochem Biophys Res Commun 355:228-33
Dancu, Michael B; Tarbell, John M (2007) Coronary endothelium expresses a pathologic gene pattern compared to aortic endothelium: correlation of asynchronous hemodynamics and pathology in vivo. Atherosclerosis 192:9-14
Dancu, Michael B; Berardi, Danielle E; Vanden Heuvel, John P et al. (2007) Atherogenic Endothelial Cell eNOS and ET-1 Responses to Asynchronous Hemodynamics are Mitigated by Conjugated Linoleic Acid. Ann Biomed Eng 35:1111-9
Dancu, Michael B; Tarbell, John M (2006) Large Negative Stress Phase Angle (SPA) attenuates nitric oxide production in bovine aortic endothelial cells. J Biomech Eng 128:329-34

Showing the most recent 10 out of 57 publications