Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL036634-10
Application #
2218243
Study Section
Cardiovascular and Renal Study Section (CVB)
Project Start
1990-04-01
Project End
1997-06-30
Budget Start
1996-04-01
Budget End
1997-06-30
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Mayo Clinic, Rochester
Department
Type
DUNS #
City
Rochester
State
MN
Country
United States
Zip Code
55905
Kawakami, Rika; Lee, Candace Y W; Scott, Christopher et al. (2018) A Human Study to Evaluate Safety, Tolerability, and Cyclic GMP Activating Properties of Cenderitide in Subjects With Stable Chronic Heart Failure. Clin Pharmacol Ther 104:546-552
Ichiki, Tomoko; Dzhoyashvili, Nina; Burnett Jr, John C (2018) Natriuretic peptide based therapeutics for heart failure: Cenderitide: A novel first-in-class designer natriuretic peptide. Int J Cardiol :
Chen, Yang; Burnett, John C (2018) Particulate Guanylyl Cyclase A/cGMP Signaling Pathway in the Kidney: Physiologic and Therapeutic Indications. Int J Mol Sci 19:
Lee, Candace Y W; Huntley, Brenda K; McCormick, Daniel J et al. (2016) Cenderitide: structural requirements for the creation of a novel dual particulate guanylyl cyclase receptor agonist with renal-enhancing in vivo and ex vivo actions. Eur Heart J Cardiovasc Pharmacother 2:98-105
Meems, Laura M G; Burnett Jr, John C (2016) Innovative Therapeutics: Designer Natriuretic Peptides. JACC Basic Transl Sci 1:557-567
Holditch, Sara J; Schreiber, Claire A; Burnett, John C et al. (2016) Arterial Remodeling in B-Type Natriuretic Peptide Knock-Out Females. Sci Rep 6:25623
Huntley, Brenda K; Sandberg, Sharon M; Heublein, Denise M et al. (2015) Pro-B-type natriuretic peptide-1-108 processing and degradation in human heart failure. Circ Heart Fail 8:89-97
Holditch, Sara J; Schreiber, Claire A; Nini, Ryan et al. (2015) B-Type Natriuretic Peptide Deletion Leads to Progressive Hypertension, Associated Organ Damage, and Reduced Survival: Novel Model for Human Hypertension. Hypertension 66:199-210
Sangaralingham, S Jeson; McKie, Paul M; Ichiki, Tomoko et al. (2015) Circulating C-type natriuretic peptide and its relationship to cardiovascular disease in the general population. Hypertension 65:1187-94
Pereira, Naveen L; Tosakulwong, Nirubol; Scott, Christopher G et al. (2015) Circulating atrial natriuretic peptide genetic association study identifies a novel gene cluster associated with stroke in whites. Circ Cardiovasc Genet 8:141-9

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