Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL039286-10
Application #
2219226
Study Section
Cardiovascular and Renal Study Section (CVB)
Project Start
1989-01-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Pennsylvania State University
Department
Biomedical Engineering
Type
Schools of Engineering
DUNS #
City
University Park
State
PA
Country
United States
Zip Code
16802
Lipowsky, Herbert H; Bowers, Daniel T; Banik, Brittany L et al. (2018) Mesenchymal Stem Cell Deformability and Implications for Microvascular Sequestration. Ann Biomed Eng 46:640-654
Lipowsky, Herbert H; Lescanic, Anne (2017) Inhibition of inflammation induced shedding of the endothelial glycocalyx with low molecular weight heparin. Microvasc Res 112:72-78
Lipowsky, Herbert H; Lescanic, Anne; Sah, Rachna (2015) Role of matrix metalloproteases in the kinetics of leukocyte-endothelial adhesion in post-capillary venules. Biorheology 52:433-45
Lipowsky, Herbert H; Lescanic, Anne (2013) Shear-dependent adhesion of leukocytes and lectins to the endothelium and concurrent changes in thickness of the glycocalyx of post-capillary venules in the low-flow state. Microcirculation 20:149-57
Lipowsky, Herbert H (2013) In vivo studies of blood rheology in the microcirculation in an in vitro world: Past, present and future. Biorheology 50:3-16
Lipowsky, Herbert H; Lescanic, Anne (2013) The effect of doxycycline on shedding of the glycocalyx due to reactive oxygen species. Microvasc Res 90:80-5
Lipowsky, Herbert H (2012) The endothelial glycocalyx as a barrier to leukocyte adhesion and its mediation by extracellular proteases. Ann Biomed Eng 40:840-8
Lipowsky, Herbert H; Gao, Lujia; Lescanic, Ann (2011) Shedding of the endothelial glycocalyx in arterioles, capillaries, and venules and its effect on capillary hemodynamics during inflammation. Am J Physiol Heart Circ Physiol 301:H2235-45
Lipowsky, Herbert H; Sah, Rachna; Lescanic, Anne (2011) Relative roles of doxycycline and cation chelation in endothelial glycan shedding and adhesion of leukocytes. Am J Physiol Heart Circ Physiol 300:H415-22
Lipowsky, Herbert H (2011) Protease Activity and the Role of the Endothelial Glycocalyx in Inflammation. Drug Discov Today Dis Models 8:57-62

Showing the most recent 10 out of 38 publications