Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
2R01HL041320-10
Application #
2461715
Study Section
Special Emphasis Panel (ZRG2-PHY (01))
Project Start
1988-07-01
Project End
1998-05-31
Budget Start
1998-01-01
Budget End
1998-05-31
Support Year
10
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Wayne State University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
Detroit
State
MI
Country
United States
Zip Code
48202
Fisher, J H; Sheftelyevich, V; Ho, Y S et al. (2000) Pulmonary-specific expression of SP-D corrects pulmonary lipid accumulation in SP-D gene-targeted mice. Am J Physiol Lung Cell Mol Physiol 278:L365-73
Wert, S E; Yoshida, M; LeVine, A M et al. (2000) Increased metalloproteinase activity, oxidant production, and emphysema in surfactant protein D gene-inactivated mice. Proc Natl Acad Sci U S A 97:5972-7
Korfhagen, T R; Sheftelyevich, V; Burhans, M S et al. (1998) Surfactant protein-D regulates surfactant phospholipid homeostasis in vivo. J Biol Chem 273:28438-43
Fisher, J H; Mason, R (1995) Expression of pulmonary surfactant protein D in rat gastric mucosa. Am J Respir Cell Mol Biol 12:13-8
Kinnard, W V; Tuder, R; Papst, P et al. (1994) Regulation of alveolar type II cell differentiation and proliferation in adult rat lung explants. Am J Respir Cell Mol Biol 11:416-25
Deterding, R R; Shimizu, H; Fisher, J H et al. (1994) Regulation of surfactant protein D expression by glucocorticoids in vitro and in vivo. Am J Respir Cell Mol Biol 10:30-7
Stelzner, T J; O'Brien, R F; Yanagisawa, M et al. (1992) Increased lung endothelin-1 production in rats with idiopathic pulmonary hypertension. Am J Physiol 262:L614-20
Shimizu, H; Fisher, J H; Papst, P et al. (1992) Primary structure of rat pulmonary surfactant protein D. cDNA and deduced amino acid sequence. J Biol Chem 267:1853-7
Fisher, J H; McCormack, F; Park, S S et al. (1991) In vivo regulation of surfactant proteins by glucocorticoids. Am J Respir Cell Mol Biol 5:63-70
Hendrickson, D J; Fisher, J H; Jones, C et al. (1990) Regional localization of human extracellular superoxide dismutase gene to 4pter-q21. Genomics 8:736-8

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