Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
7R01HL042665-08
Application #
2220637
Study Section
Cardiovascular and Renal Study Section (CVB)
Project Start
1989-04-01
Project End
1999-03-31
Budget Start
1996-02-01
Budget End
1996-03-31
Support Year
8
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Saint Louis University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
City
Saint Louis
State
MO
Country
United States
Zip Code
63103
Faustino, Randolph S; Stronger, Lyle N W; Richard, Melanie N et al. (2007) RanGAP-mediated nuclear protein import in vascular smooth muscle cells is augmented by lysophosphatidylcholine. Mol Pharmacol 71:438-45
Thukkani, Arun K; Martinson, Bradley D; Albert, Carolyn J et al. (2005) Neutrophil-mediated accumulation of 2-ClHDA during myocardial infarction: 2-ClHDA-mediated myocardial injury. Am J Physiol Heart Circ Physiol 288:H2955-64
Albert, Carolyn J; Thukkani, Arun K; Heuertz, Rita M et al. (2003) Eosinophil peroxidase-derived reactive brominating species target the vinyl ether bond of plasmalogens generating a novel chemoattractant, alpha-bromo fatty aldehyde. J Biol Chem 278:8942-50
Hsu, Fong-Fu; Turk, John; Thukkani, Arun K et al. (2003) Characterization of alkylacyl, alk-1-enylacyl and lyso subclasses of glycerophosphocholine by tandem quadrupole mass spectrometry with electrospray ionization. J Mass Spectrom 38:752-63
Ford, David A (2003) Separate myocardial ethanolamine phosphotransferase activities responsible for plasmenylethanolamine and phosphatidylethanolamine synthesis. J Lipid Res 44:554-9
Thukkani, Arun K; McHowat, Jane; Hsu, Fong-Fu et al. (2003) Identification of alpha-chloro fatty aldehydes and unsaturated lysophosphatidylcholine molecular species in human atherosclerotic lesions. Circulation 108:3128-33
Thukkani, Arun K; Albert, Carolyn J; Wildsmith, Kristin R et al. (2003) Myeloperoxidase-derived reactive chlorinating species from human monocytes target plasmalogens in low density lipoprotein. J Biol Chem 278:36365-72
Thukkani, Arun K; Hsu, Fong-Fu; Crowley, Jan R et al. (2002) Reactive chlorinating species produced during neutrophil activation target tissue plasmalogens: production of the chemoattractant, 2-chlorohexadecanal. J Biol Chem 277:3842-9
Albert, Carolyn J; Crowley, Jan R; Hsu, Fong-Fu et al. (2002) Reactive brominating species produced by myeloperoxidase target the vinyl ether bond of plasmalogens: disparate utilization of sodium halides in the production of alpha-halo fatty aldehydes. J Biol Chem 277:4694-703
Chiu, H C; Kovacs, A; Ford, D A et al. (2001) A novel mouse model of lipotoxic cardiomyopathy. J Clin Invest 107:813-22

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