This grant application is aimed at improving the understanding of the contribution of impaired T cell production to the effects of HIV. First, the investigator will examineif there is impairment in lymphopoietic capacity of HIV+ bone marrows. Second, the investigator will examine the expression of gene products that regulate hematopoiesis. Third, the investigator will examine the effects of AIDS medications on T cell production.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL044851-09
Application #
6043765
Study Section
AIDS and Related Research Study Section 3 (ARRC)
Project Start
1991-02-01
Project End
2001-07-31
Budget Start
1999-08-01
Budget End
2000-07-31
Support Year
9
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199
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