Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL047014-04
Application #
2223329
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1992-08-01
Project End
1996-11-30
Budget Start
1995-07-01
Budget End
1996-11-30
Support Year
4
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Oklahoma Medical Research Foundation
Department
Type
DUNS #
937727907
City
Oklahoma City
State
OK
Country
United States
Zip Code
73104
Gajsiewicz, Joshua M; Smith, Stephanie A; Morrissey, James H (2017) Polyphosphate and RNA Differentially Modulate the Contact Pathway of Blood Clotting. J Biol Chem 292:1808-1814
Smith, Stephanie A; Baker, Catherine J; Gajsiewicz, Joshua M et al. (2017) Silica particles contribute to the procoagulant activity of DNA and polyphosphate isolated using commercial kits. Blood 130:88-91
Kalathottukaren, Manu Thomas; Abraham, Libin; Kapopara, Piyushkumar R et al. (2017) Alteration of blood clotting and lung damage by protamine are avoided using the heparin and polyphosphate inhibitor UHRA. Blood 129:1368-1379
Sylman, Joanna L; Daalkhaijav, Uranbileg; Zhang, Ying et al. (2017) Differential Roles for the Coagulation Factors XI and XII in Regulating the Physical Biology of Fibrin. Ann Biomed Eng 45:1328-1340
Puy, Cristina; Tucker, Erik I; Ivanov, Ivan S et al. (2016) Platelet-Derived Short-Chain Polyphosphates Enhance the Inactivation of Tissue Factor Pathway Inhibitor by Activated Coagulation Factor XI. PLoS One 11:e0165172
Wijeyewickrema, Lakshmi C; Lameignere, Emilie; Hor, Lilian et al. (2016) Polyphosphate is a novel cofactor for regulation of complement by a serpin, C1 inhibitor. Blood 128:1766-76
Zilberman-Rudenko, Jevgenia; Itakura, Asako; Wiesenekker, Chantal P et al. (2016) Coagulation Factor XI Promotes Distal Platelet Activation and Single Platelet Consumption in the Bloodstream Under Shear Flow. Arterioscler Thromb Vasc Biol 36:510-7
Choi, Sharon H; Smith, Stephanie A; Morrissey, James H (2015) Polyphosphate accelerates factor V activation by factor XIa. Thromb Haemost 113:599-604
Hassanian, S M; Dinarvand, P; Smith, S A et al. (2015) Inorganic polyphosphate elicits pro-inflammatory responses through activation of the mammalian target of rapamycin complexes 1 and 2 in vascular endothelial cells. J Thromb Haemost 13:860-71
Travers, R J; Smith, S A; Morrissey, J H (2015) Polyphosphate, platelets, and coagulation. Int J Lab Hematol 37 Suppl 1:31-5

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