Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL047619-05
Application #
2223809
Study Section
Mammalian Genetics Study Section (MGN)
Project Start
1992-02-01
Project End
2000-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas Sw Medical Center Dallas
Department
Genetics
Type
Schools of Medicine
DUNS #
City
Dallas
State
TX
Country
United States
Zip Code
75390
Guerra, Rudy; Yu, Zhaoxia; Marcovina, Santica et al. (2005) Lipoprotein(a) and apolipoprotein(a) isoforms: no association with coronary artery calcification in the Dallas Heart Study. Circulation 111:1471-9
Arca, Marcello; Zuliani, Giovanni; Wilund, Kenneth et al. (2002) Autosomal recessive hypercholesterolaemia in Sardinia, Italy, and mutations in ARH: a clinical and molecular genetic analysis. Lancet 359:841-7
Wang, J; Boedeker, J; Hobbs, H H et al. (2001) Determinants of human apolipoprotein [a] secretion from mouse hepatocyte cultures. J Lipid Res 42:60-9
Acquati, F; Hammer, R; Ercoli, B et al. (1999) Transgenic mice expressing a human apolipoprotein[a] allele. J Lipid Res 40:994-1006
Tao, R; Acquati, F; Marcovina, S M et al. (1999) Human growth hormone increases apo(a) expression in transgenic mice. Arterioscler Thromb Vasc Biol 19:2439-47
Hobbs, H H; White, A L (1999) Lipoprotein(a): intrigues and insights. Curr Opin Lipidol 10:225-36
Mooser, V; Scheer, D; Marcovina, S M et al. (1997) The Apo(a) gene is the major determinant of variation in plasma Lp(a) levels in African Americans. Am J Hum Genet 61:402-17
Mooser, V; Marcovina, S M; Wang, J et al. (1997) High plasma levels of apo(a) fragments in Caucasians and African-Americans with end-stage renal disease: implications for plasma Lp(a) assay. Clin Genet 52:387-92
Marcovina, S M; Hobbs, H H; Albers, J J (1996) Relation between number of apolipoprotein(a) kringle 4 repeats and mobility of isoforms in agarose gel: basis for a standardized isoform nomenclature. Clin Chem 42:436-9
Mooser, V; Marcovina, S M; White, A L et al. (1996) Kringle-containing fragments of apolipoprotein(a) circulate in human plasma and are excreted into the urine. J Clin Invest 98:2414-24

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