Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL048282-08
Application #
6638331
Study Section
Lung Biology and Pathology Study Section (LBPA)
Program Officer
Banks-Schlegel, Susan P
Project Start
1995-01-01
Project End
2005-05-31
Budget Start
2003-06-01
Budget End
2004-05-31
Support Year
8
Fiscal Year
2003
Total Cost
$294,000
Indirect Cost
Name
University of Nebraska Medical Center
Department
Biochemistry
Type
Schools of Medicine
DUNS #
168559177
City
Omaha
State
NE
Country
United States
Zip Code
68198
Chachadi, Vishwanath B; Bhat, Ganapati; Cheng, Pi-Wan (2015) Glycosyltransferases involved in the synthesis of MUC-associated metastasis-promoting selectin ligands. Glycobiology 25:963-75
Chachadi, Vishwanath B; Ali, Mohamed F; Cheng, Pi-Wan (2013) Prostatic cell-specific regulation of the synthesis of MUC1-associated sialyl Lewis a. PLoS One 8:e57416
Petrosyan, Armen; Cheng, Pi-Wan (2013) A non-enzymatic function of Golgi glycosyltransferases: mediation of Golgi fragmentation by interaction with non-muscle myosin IIA. Glycobiology 23:690-708
Gao, Yin; Chachadi, Vishwanath B; Cheng, Pi-Wan et al. (2012) Glycosylation potential of human prostate cancer cell lines. Glycoconj J 29:525-37
Ali, Mohamed F; Chachadi, Vishwanath B; Petrosyan, Armen et al. (2012) Golgi phosphoprotein 3 determines cell binding properties under dynamic flow by controlling Golgi localization of core 2 N-acetylglucosaminyltransferase 1. J Biol Chem 287:39564-77
Petrosyan, Armen; Ali, Mohamed F; Verma, Shailendra Kumar et al. (2012) Non-muscle myosin IIA transports a Golgi glycosyltransferase to the endoplasmic reticulum by binding to its cytoplasmic tail. Int J Biochem Cell Biol 44:1153-65
Petrosyan, Armen; Ali, Mohamed F; Cheng, Pi-Wan (2012) Glycosyltransferase-specific Golgi-targeting mechanisms. J Biol Chem 287:37621-7
Radhakrishnan, Prakash; Chachadi, Vishwanath; Lin, Ming-Fong et al. (2011) TNF? enhances the motility and invasiveness of prostatic cancer cells by stimulating the expression of selective glycosyl- and sulfotransferase genes involved in the synthesis of selectin ligands. Biochem Biophys Res Commun 409:436-41
Chachadi, Vishwanath B; Cheng, Helen; Klinkebiel, David et al. (2011) 5-Aza-2'-deoxycytidine increases sialyl Lewis X on MUC1 by stimulating ?-galactoside:?2,3-sialyltransferase 6 gene. Int J Biochem Cell Biol 43:586-93
Cheng, Pi-Wan; Radhakrishnan, Prakash (2011) Mucin O-glycan branching enzymes: structure, function, and gene regulation. Adv Exp Med Biol 705:465-92

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