Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
3R01HL048411-01A1S1
Application #
3367550
Study Section
Toxicology Subcommittee 2 (TOX)
Project Start
1993-01-01
Project End
1997-12-31
Budget Start
1993-01-01
Budget End
1993-12-31
Support Year
1
Fiscal Year
1993
Total Cost
Indirect Cost
Name
University of California Davis
Department
Type
Schools of Veterinary Medicine
DUNS #
094878337
City
Davis
State
CA
Country
United States
Zip Code
95618
Nakayama Wong, Lynn S; Lame, Michael W; Jones, A Daniel et al. (2010) Differential cellular responses to protein adducts of naphthoquinone and monocrotaline pyrrole. Chem Res Toxicol 23:1504-13
Ramos, M; Lame, M W; Segall, H J et al. (2007) Monocrotaline pyrrole induces Smad nuclear accumulation and altered signaling expression in human pulmonary arterial endothelial cells. Vascul Pharmacol 46:439-48
Eiselein, Larissa; Wilson, Dennis W; Lame, Michael W et al. (2007) Lipolysis products from triglyceride-rich lipoproteins increase endothelial permeability, perturb zonula occludens-1 and F-actin, and induce apoptosis. Am J Physiol Heart Circ Physiol 292:H2745-53
Ramos, M; Lame, M W; Segall, H J et al. (2006) The BMP type II receptor is located in lipid rafts, including caveolae, of pulmonary endothelium in vivo and in vitro. Vascul Pharmacol 44:50-9
Zabka, T S; Campbell, F E; Wilson, D W (2006) Pulmonary arteriopathy and idiopathic pulmonary arterial hypertension in six dogs. Vet Pathol 43:510-22
Lame, Michael W; Jones, A Daniel; Wilson, Dennis W et al. (2005) Monocrotaline pyrrole targets proteins with and without cysteine residues in the cytosol and membranes of human pulmonary artery endothelial cells. Proteomics 5:4398-413
Lame, Michael W; Jones, A Daniel; Wilson, Dennis W et al. (2003) Protein targets of 1,4-benzoquinone and 1,4-naphthoquinone in human bronchial epithelial cells. Proteomics 3:479-95
Taylor, Debra W; Lame, Michael W; Nakayama, Lynn S et al. (2003) Effects of monocrotaline pyrrole and thrombin on pulmonary endothelial cell junction and matrix adhesion proteins. Toxicology 184:227-40
Finney, Montenique L; Stoney, Catherine M; Engebretson, Tilmer O (2002) Hostility and anger expression in African American and European American men is associated with cardiovascular and lipid reactivity. Psychophysiology 39:340-9
Stoney, Catherine M; West, Sheila G; Hughes, Joel W et al. (2002) Acute psychological stress reduces plasma triglyceride clearance. Psychophysiology 39:80-5

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