Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL051134-02
Application #
2227676
Study Section
Lung Biology and Pathology Study Section (LBPA)
Project Start
1994-12-01
Project End
1999-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Duke University
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
071723621
City
Durham
State
NC
Country
United States
Zip Code
27705
Geunes-Boyer, Scarlett; Beers, Michael F; Perfect, John R et al. (2012) Surfactant protein D facilitates Cryptococcus neoformans infection. Infect Immun 80:2444-53
Goto, Hisatsugu; Ledford, Julie G; Mukherjee, Sambuddho et al. (2010) The role of surfactant protein A in bleomycin-induced acute lung injury. Am J Respir Crit Care Med 181:1336-44
Geunes-Boyer, Scarlett; Oliver, Timothy N; Janbon, Guilhem et al. (2009) Surfactant protein D increases phagocytosis of hypocapsular Cryptococcus neoformans by murine macrophages and enhances fungal survival. Infect Immun 77:2783-94
Giles, Steven S; Zaas, Aimee K; Reidy, Mike F et al. (2007) Cryptococcus neoformans is resistant to surfactant protein A mediated host defense mechanisms. PLoS One 2:e1370
Pastva, Amy M; Wright, Jo Rae; Williams, Kristi L (2007) Immunomodulatory roles of surfactant proteins A and D: implications in lung disease. Proc Am Thorac Soc 4:252-7
Wofford, Jessica A; Wright, Jo Rae (2007) Surfactant protein A regulates IgG-mediated phagocytosis in inflammatory neutrophils. Am J Physiol Lung Cell Mol Physiol 293:L1437-43
Wright, Jo Rae (2006) The ""wisdom"" of lung surfactant: balancing host defense and surface tension-reducing functions. Am J Physiol Lung Cell Mol Physiol 291:L847-50
Lin, Peggy M; Wright, Jo Rae (2006) Surfactant protein A binds to IgG and enhances phagocytosis of IgG-opsonized erythrocytes. Am J Physiol Lung Cell Mol Physiol 291:L1199-206
Malloy, Jaret L; Veldhuizen, Ruud A W; Thibodeaux, Brett A et al. (2005) Pseudomonas aeruginosa protease IV degrades surfactant proteins and inhibits surfactant host defense and biophysical functions. Am J Physiol Lung Cell Mol Physiol 288:L409-18
Alcorn, John F; Wright, Jo Rae (2004) Surfactant protein A inhibits alveolar macrophage cytokine production by CD14-independent pathway. Am J Physiol Lung Cell Mol Physiol 286:L129-36

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