Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL052234-02
Application #
2229510
Study Section
Nutrition Study Section (NTN)
Project Start
1994-12-01
Project End
1997-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Cleveland Clinic Lerner
Department
Type
DUNS #
017730458
City
Cleveland
State
OH
Country
United States
Zip Code
44195
Hannibal, Luciana; DiBello, Patricia M; Jacobsen, Donald W (2013) Proteomics of vitamin B12 processing. Clin Chem Lab Med 51:477-88
Metes-Kosik, Nicole; Luptak, Ivan; Dibello, Patricia M et al. (2012) Both selenium deficiency and modest selenium supplementation lead to myocardial fibrosis in mice via effects on redox-methylation balance. Mol Nutr Food Res 56:1812-24
Moreira, Edward S; Brasch, Nicola E; Yun, June (2011) Vitamin B12 protects against superoxide-induced cell injury in human aortic endothelial cells. Free Radic Biol Med 51:876-83
Hannibal, Luciana; DiBello, Patricia M; Yu, Michelle et al. (2011) The MMACHC proteome: hallmarks of functional cobalamin deficiency in humans. Mol Genet Metab 103:226-39
Tsitsiou, Eleni; Sibley, Colin P; D'Souza, Stephen W et al. (2011) Homocysteine is transported by the microvillous plasma membrane of human placenta. J Inherit Metab Dis 34:57-65
Al-Hashimi, Ali A; Caldwell, Jennifer; Gonzalez-Gronow, Mario et al. (2010) Binding of anti-GRP78 autoantibodies to cell surface GRP78 increases tissue factor procoagulant activity via the release of calcium from endoplasmic reticulum stores. J Biol Chem 285:28912-23
Quadros, Edward V; Lai, Shao-Chiang; Nakayama, Yasumi et al. (2010) Positive newborn screen for methylmalonic aciduria identifies the first mutation in TCblR/CD320, the gene for cellular uptake of transcobalamin-bound vitamin B(12). Hum Mutat 31:924-9
DiBello, Patricia M; Dayal, Sanjana; Kaveti, Suma et al. (2010) The nutrigenetics of hyperhomocysteinemia: quantitative proteomics reveals differences in the methionine cycle enzymes of gene-induced versus diet-induced hyperhomocysteinemia. Mol Cell Proteomics 9:471-85
Hannibal, Luciana; Smith, Clyde A; Jacobsen, Donald W (2010) The X-ray crystal structure of glutathionylcobalamin revealed. Inorg Chem 49:9921-7
Chen, Xiaocong; Sebastian, Becky M; Tang, Hui et al. (2009) Taurine supplementation prevents ethanol-induced decrease in serum adiponectin and reduces hepatic steatosis in rats. Hepatology 49:1554-62

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