Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL052555-02
Application #
2229987
Study Section
Cardiovascular and Pulmonary Research A Study Section (CVA)
Project Start
1995-08-01
Project End
2000-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Baylor College of Medicine
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
074615394
City
Houston
State
TX
Country
United States
Zip Code
77030
Chuang, Huai-Chia; Sheu, Wayne H-H; Lin, Yi-Ting et al. (2014) HGK/MAP4K4 deficiency induces TRAF2 stabilization and Th17 differentiation leading to insulin resistance. Nat Commun 5:4602
Greenblatt, Matthew B; Shim, Jae-Hyuck; Zou, Weiguo et al. (2010) The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice. J Clin Invest 120:2457-73
Shim, Jae-Hyuck; Greenblatt, Matthew B; Xie, Min et al. (2009) TAK1 is an essential regulator of BMP signalling in cartilage. EMBO J 28:2028-41
Charng, M J; Zhang, D; Kinnunen, P et al. (1998) A novel protein distinguishes between quiescent and activated forms of the type I transforming growth factor beta receptor. J Biol Chem 273:9365-8
Abdellatif, M; Packer, S E; Michael, L H et al. (1998) A Ras-dependent pathway regulates RNA polymerase II phosphorylation in cardiac myocytes: implications for cardiac hypertrophy. Mol Cell Biol 18:6729-36
Agah, R; Kirshenbaum, L A; Abdellatif, M et al. (1997) Adenoviral delivery of E2F-1 directs cell cycle reentry and p53-independent apoptosis in postmitotic adult myocardium in vivo. J Clin Invest 100:2722-8
MacLellan, W R; Schneider, M D (1997) Death by design. Programmed cell death in cardiovascular biology and disease. Circ Res 81:137-44
Agah, R; Frenkel, P A; French, B A et al. (1997) Gene recombination in postmitotic cells. Targeted expression of Cre recombinase provokes cardiac-restricted, site-specific rearrangement in adult ventricular muscle in vivo. J Clin Invest 100:169-79
Charng, M J; Kinnunen, P; Hawker, J et al. (1996) FKBP-12 recognition is dispensable for signal generation by type I transforming growth factor-beta receptors. J Biol Chem 271:22941-4
Kirshenbaum, L A; Abdellatif, M; Chakraborty, S et al. (1996) Human E2F-1 reactivates cell cycle progression in ventricular myocytes and represses cardiac gene transcription. Dev Biol 179:402-11