Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL054120-02
Application #
2232358
Study Section
Human Embryology and Development Subcommittee 1 (HED)
Project Start
1995-04-01
Project End
1998-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Loma Linda University
Department
Type
Schools of Medicine
DUNS #
City
Loma Linda
State
CA
Country
United States
Zip Code
92350
Adeoye, Olayemi O; Silpanisong, Jinjutha; Williams, James M et al. (2015) Role of the sympathetic autonomic nervous system in hypoxic remodeling of the fetal cerebral vasculature. J Cardiovasc Pharmacol 65:308-16
Pearce, William J (2014) The fetal cerebral circulation: three decades of exploration by the LLU Center for Perinatal Biology. Adv Exp Med Biol 814:177-91
Durrant, Lara M; Khorram, Omid; Buchholz, John N et al. (2014) Maternal food restriction modulates cerebrovascular structure and contractility in adult rat offspring: effects of metyrapone. Am J Physiol Regul Integr Comp Physiol 306:R401-10
Adeoye, Olayemi O; Bouthors, Vincent; Hubbell, Margaret C et al. (2014) VEGF receptors mediate hypoxic remodeling of adult ovine carotid arteries. J Appl Physiol (1985) 117:777-87
Pearce, William J; Khorram, Omid (2013) Maturation and differentiation of the fetal vasculature. Clin Obstet Gynecol 56:537-48
Adeoye, Olayemi O; Butler, Stacy M; Hubbell, Margaret C et al. (2013) Contribution of increased VEGF receptors to hypoxic changes in fetal ovine carotid artery contractile proteins. Am J Physiol Cell Physiol 304:C656-65
Hubbell, Margaret C; Semotiuk, Andrew J; Thorpe, Richard B et al. (2012) Chronic hypoxia and VEGF differentially modulate abundance and organization of myosin heavy chain isoforms in fetal and adult ovine arteries. Am J Physiol Cell Physiol 303:C1090-103
Pearce, William J; Butler, Stacy M; Abrassart, Jenna M et al. (2011) Fetal cerebral oxygenation: the homeostatic role of vascular adaptations to hypoxic stress. Adv Exp Med Biol 701:225-32
Butler, Stacy M; Abrassart, Jenna M; Hubbell, Margaret C et al. (2011) Contributions of VEGF to age-dependent transmural gradients in contractile protein expression in ovine carotid arteries. Am J Physiol Cell Physiol 301:C653-66
Khorram, O; Han, G; Bagherpour, R et al. (2010) Effect of maternal undernutrition on vascular expression of micro and messenger RNA in newborn and aging offspring. Am J Physiol Regul Integr Comp Physiol 298:R1366-74

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