Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL062150-08
Application #
6184597
Study Section
Lung Biology and Pathology Study Section (LBPA)
Project Start
1993-07-10
Project End
2003-06-30
Budget Start
2000-07-01
Budget End
2001-06-30
Support Year
8
Fiscal Year
2000
Total Cost
$234,924
Indirect Cost
Name
Mayo Clinic, Rochester
Department
Type
DUNS #
City
Rochester
State
MN
Country
United States
Zip Code
55905
Kottom, Theodore J; Hebrink, Deanne M; Jenson, Paige E et al. (2018) Dectin-2 Is a C-Type Lectin Receptor that Recognizes Pneumocystis and Participates in Innate Immune Responses. Am J Respir Cell Mol Biol 58:232-240
Cheon, In Su; Son, Young Min; Jiang, Li et al. (2018) Neonatal hyperoxia promotes asthma-like features through IL-33-dependent ILC2 responses. J Allergy Clin Immunol 142:1100-1112
Burnham-Marusich, Amanda R; Hubbard, Breeana; Kvam, Alexander J et al. (2018) Conservation of Mannan Synthesis in Fungi of the Zygomycota and Ascomycota Reveals a Broad Diagnostic Target. mSphere 3:
Nandakumar, Vijayalakshmi; Hebrink, Deanne; Jenson, Paige et al. (2017) Differential Macrophage Polarization from Pneumocystis in Immunocompetent and Immunosuppressed Hosts: Potential Adjunctive Therapy during Pneumonia. Infect Immun 85:
Kottom, Theodore J; Hebrink, Deanne M; Jenson, Paige E et al. (2017) The Interaction of Pneumocystis with the C-Type Lectin Receptor Mincle Exerts a Significant Role in Host Defense against Infection. J Immunol 198:3515-3525
Kottom, Theodore J; Hebrink, Deanne M; Jenson, Paige E et al. (2017) Characterization of N-Acetylglucosamine Biosynthesis in Pneumocystis species. A New Potential Target for Therapy. Am J Respir Cell Mol Biol 56:213-222
Kottom, Theodore J; Limper, Andrew H (2016) Evidence for a Pneumocystis carinii Flo8-like transcription factor: insights into organism adhesion. Med Microbiol Immunol 205:73-84
Calero-Bernal, Maria L; Martin-Garrido, Isabel; Donazar-Ezcurra, Mikel et al. (2016) Intermittent Courses of Corticosteroids Also Present a Risk for Pneumocystis Pneumonia in Non-HIV Patients. Can Respir J 2016:2464791
Kottom, Theodore J; Hebrink, Deanne M; Jenson, Paige E et al. (2015) Evidence for Proinflammatory ?-1,6 Glucans in the Pneumocystis carinii Cell Wall. Infect Immun 83:2816-26
Ali, Mohamed F; Driscoll, Christopher B; Walters, Paula R et al. (2015) ?-Glucan-Activated Human B Lymphocytes Participate in Innate Immune Responses by Releasing Proinflammatory Cytokines and Stimulating Neutrophil Chemotaxis. J Immunol 195:5318-26

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