Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
2R01HL063209-05
Application #
6967415
Study Section
Atherosclerosis and Inflammation of the Cardiovascular System Study Section (AICS)
Project Start
2005-03-01
Project End
2010-02-28
Budget Start
Budget End
Support Year
5
Fiscal Year
2005
Total Cost
Indirect Cost
Name
University of Chicago
Department
Type
DUNS #
225410919
City
Chicago
State
IL
Country
United States
Zip Code
60637
Edelstein, Celina; Pfaffinger, Ditta; Yang, Ming et al. (2010) Naturally occurring human plasminogen, like genetically related apolipoprotein(a), contains oxidized phosphatidylcholine adducts. Biochim Biophys Acta 1801:738-45
Edelstein, Celina; Pfaffinger, Ditta; Reichert, Ethan C et al. (2010) Mouse plasminogen has oxidized phosphatidylcholine adducts that are not metabolized by lipoprotein-associated phospholipase A?under basal conditions. Int J Mol Sci 11:5339-47
Ober, Carole; Nord, Alex S; Thompson, Emma E et al. (2009) Genome-wide association study of plasma lipoprotein(a) levels identifies multiple genes on chromosome 6q. J Lipid Res 50:798-806
Lepedda, Antonio J; Cigliano, Antonio; Cherchi, Gian Mario et al. (2009) A proteomic approach to differentiate histologically classified stable and unstable plaques from human carotid arteries. Atherosclerosis 203:112-8
Scanu, Angelo M; Bamba, Ravi (2008) Niacin and lipoprotein(a): facts, uncertainties, and clinical considerations. Am J Cardiol 101:44B-47B
Scanu, Angelo M; Edelstein, Celina (2008) HDL: bridging past and present with a look at the future. FASEB J 22:4044-54
Edelstein, Celina; Yousef, Mohammed; Scanu, Angelo M (2005) Elements in the C terminus of apolipoprotein [a] responsible for the binding to the tenth type III module of human fibronectin. J Lipid Res 46:2673-80
Scanu, Angelo M; Hinman, Janet; Pfaffinger, Ditta et al. (2004) Successful utilization of lyophilized lipoprotein(a) as a biological reagent. Lipids 39:589-93
Edelstein, Celina; Pfaffinger, Ditta; Hinman, Janet et al. (2003) Lysine-phosphatidylcholine adducts in kringle V impart unique immunological and potential pro-inflammatory properties to human apolipoprotein(a). J Biol Chem 278:52841-7
Scanu, Angelo M (2003) Lipoprotein(a) and the atherothrombotic process: mechanistic insights and clinical implications. Curr Atheroscler Rep 5:106-13

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