This longitudinal community study of young adults builds on a comprehensive data base of behavioral, social, health, familial, and academic measures collected at five timepoints from early childhood (age 5) to late adolescence (age 18). Continued study of this community sample at age 21 or 22 is important because young adulthood is a critical, but little studied, transitional period for the establishment of occupational choices, educational status, and social relations. This young adult period is complicated by a heightened risk for psychiatric disorders which may interfere with the successful acquisition of these adult roles. This study offers the rare opportunity to trace the onset, course, and consequences of disorders in a representative community sample by examining data collected over a 17-year span. Emphasis will be placed on the identification of those early psychosocial risks for disorders that can offer specific implications for targeted intervention and prevention efforts.
Specific aims of the study are to: (1) determine the frequency and age of onset of selected DSM-III-R psychiatric disorders in young adults and identify early risks associated with onset; (2) examine the comorbidity (co-occurrence) of disorders in young adults, as well as the risks for and consequences of comorbidity; (3) identify psychosocial factors associated with the remission and continuity of disorders, suicidal ideation, and behavior problems; and (4) assess the impact of psychiatric disorders on young adult functioning. Beginning in the fall of 1993, approximately 350 of the 386 young adults (90%) last interviewed at age 18 will be re-interviewed by trained interviewers who have clinical experience. The 2-hour structured interview will include the DIS-III-R to assess psychiatric disorders, as well as questions about life events, vocational and educational status and goals, health, and interpersonal relationships. Young adults will also complete a battery of standardized instruments designed to measure self-esteem, perceived mastery, family cohesion, behavior problems, and social support. In addition, the mothers of these young adults will be interviewed about family history of disorders using the FH-RDC. Hypothesized relationships between risk factors and disorders, drawn from the literature as well as prior analyses of this study group, will be examined through univariate and multivariate techniques including logistic regression, survival analysis, and longitudinal random effects models. Findings will make several substantive contributions about the frequency, onset, comorbidity and impact of psychiatric disorders in young adults. In addition, the study's emphasis on the identification of early psychosocial risks for disorders will contribute to effective planning for programs aimed at prevention and early intervention.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH041569-09
Application #
2245204
Study Section
Epidemiology and Genetics Review Committee (EPI)
Project Start
1987-01-01
Project End
1996-12-31
Budget Start
1995-01-01
Budget End
1995-12-31
Support Year
9
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Simmons College
Department
Type
Schools of Social Work
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02115
Paradis, Angela D; Giaconia, Rose M; Reinherz, Helen Z et al. (2011) Adolescent Family Factors Promoting Healthy Adult Functioning: A Longitudinal Community Study. Child Adolesc Ment Health 16:30-37
Tanner, Jennifer L; Reinherz, Helen Z; Beardslee, William R et al. (2007) Change in prevalence of psychiatric disorders from ages 21 to 30 in a community sample. J Nerv Ment Dis 195:298-306
Reinherz, Helen Z; Tanner, Jennifer L; Berger, Sasha R et al. (2006) Adolescent suicidal ideation as predictive of psychopathology, suicidal behavior, and compromised functioning at age 30. Am J Psychiatry 163:1226-32
Paradis, Angela D; Reinherz, Helen Z; Giaconia, Rose M et al. (2006) Major depression in the transition to adulthood: the impact of active and past depression on young adult functioning. J Nerv Ment Dis 194:318-23
Reinherz, Helen Z; Paradis, Angela D; Giaconia, Rose M et al. (2003) Childhood and adolescent predictors of major depression in the transition to adulthood. Am J Psychiatry 160:2141-7
Giaconia, R M; Reinherz, H Z; Paradis, A D et al. (2001) Major depression and drug disorders in adolescence: general and specific impairments in early adulthood. J Am Acad Child Adolesc Psychiatry 40:1426-33
Reinherz, H Z; Giaconia, R M; Hauf, A M et al. (2000) General and specific childhood risk factors for depression and drug disorders by early adulthood. J Am Acad Child Adolesc Psychiatry 39:223-31
Giaconia, R M; Reinherz, H Z; Hauf, A C et al. (2000) Comorbidity of substance use and post-traumatic stress disorders in a community sample of adolescents. Am J Orthopsychiatry 70:253-62
Frost, A K; Reinherz, H Z; Pakiz-Camras, B et al. (1999) Risk factors for depressive symptoms in late adolescence: a longitudinal community study. Am J Orthopsychiatry 69:370-81
Reinherz, H Z; Giaconia, R M; Hauf, A M et al. (1999) Major depression in the transition to adulthood: risks and impairments. J Abnorm Psychol 108:500-10

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