New insights are needed in order for parents and practitioners to deal more effectively with juvenile disruptive behavior, delinquency, substance use, their comorbid conditions, and long-term sequelae. Longitudinal studies are one of the best tools to generate new knowledge about these vexing problems. The Pittsburgh Youth Study (N = 1,517) is now in its sixth year with data collected from target boys, their parent, and their teachers, and has achieved a high cooperation rate. This proposal aims at building a data base relevant for optimizing future preventive interventions. For that purpose the study proposes the continued follow-up of 506 subjects for another two data waves, spread over four years.
The first aim i s to examine the developmental course and prevalence of disruptive and antisocial behavior from ages 7 to 20, including the documentation of the sequence of onsets of problem behaviors (and the late onset of such behaviors), to trace developmental progressions in disruptive behavior, to examine long-term sequelae, and to identify developmental sequences leading to cessation of disruptive behavior.
The second aim i s to study the influence of comorbid conditions (attention-deficit/hyperactivity, anxiety, depression, substance use, and learning problems) on the course and outcome of juvenile disruptive behavior.
The third aim addresses risk and protective factors relevant for the etiology of disruptive behavior, and examines the degree of specificity of such factors for different disorders and comorbid conditions. Finally, the study aims at elucidating subjects' and caretakers' help-seeking for mental health and other problems. The study measures a variety of risk and potential protective factors, the stability and change of these factors as they are likely to affect the development of different manifestations of disruptive behavior over time. Analytic aims are to narrow down those risk factors which can best explain different developmental processes, such as initiation, escalation, and desistance, and which can best account for individual differences in subjects' travelling on different pathways toward antisocial behavior. Analyses will make extensive use of data collected over the past five year and, together with the new data, will form the basis of analytic strategies geared at generating new knowledge to optimize future interventions, such as the identification of developmental pathways, the timing of risk factors, the interaction between these factors, and the identification of protective factors potentially amenable for prevention.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH050778-07
Application #
2873053
Study Section
Child Psychopathology and Treatment Review Committee (CPT)
Program Officer
Tuma, Farris K
Project Start
1993-05-01
Project End
2002-01-31
Budget Start
1999-02-01
Budget End
2000-01-31
Support Year
7
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Psychiatry
Type
Schools of Medicine
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
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