Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
1R01MH056838-01
Application #
2035483
Study Section
AIDS and Related Research Study Section 7 (ARRG)
Project Start
1996-09-30
Project End
2000-04-30
Budget Start
1996-09-30
Budget End
1997-04-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Rochester
Department
Neurology
Type
Schools of Dentistry
DUNS #
208469486
City
Rochester
State
NY
Country
United States
Zip Code
14627

  Publications

Bellizzi, Matthew J; Geathers, Jasmine S; Allan, Kevin C et al. (2016) Platelet-Activating Factor Receptors Mediate Excitatory Postsynaptic Hippocampal Injury in Experimental Autoimmune Encephalomyelitis. J Neurosci 36:1336-46
Zhang, Gang; Guo, Dongwei; Dash, Prasanta K et al. (2016) The mixed lineage kinase-3 inhibitor URMC-099 improves therapeutic outcomes for long-acting antiretroviral therapy. Nanomedicine 12:109-22
Puccini, Jenna M; Marker, Daniel F; Fitzgerald, Tim et al. (2015) Leucine-rich repeat kinase 2 modulates neuroinflammation and neurotoxicity in models of human immunodeficiency virus 1-associated neurocognitive disorders. J Neurosci 35:5271-83
Tremblay, Marie-Ève; Marker, Daniel F; Puccini, Jenna M et al. (2013) Ultrastructure of microglia-synapse interactions in the HIV-1 Tat-injected murine central nervous system. Commun Integr Biol 6:e27670
Gelbard, Harris A; Gendelman, Howard E (2013) Lipids and cognition make good bedfellows for neuroAIDS. Neurology 81:1480-1
Marker, Daniel F; Tremblay, Marie-Ève; Puccini, Jenna M et al. (2013) The new small-molecule mixed-lineage kinase 3 inhibitor URMC-099 is neuroprotective and anti-inflammatory in models of human immunodeficiency virus-associated neurocognitive disorders. J Neurosci 33:9998-10010
Marker, Daniel F; Puccini, Jenna M; Mockus, Taryn E et al. (2012) LRRK2 kinase inhibition prevents pathological microglial phagocytosis in response to HIV-1 Tat protein. J Neuroinflammation 9:261
Lu, Shao-Ming; Tremblay, Marie-Ève; King, Irah L et al. (2011) HIV-1 Tat-induced microgliosis and synaptic damage via interactions between peripheral and central myeloid cells. PLoS One 6:e23915
Perry, Seth W; Norman, John P; Barbieri, Justin et al. (2011) Mitochondrial membrane potential probes and the proton gradient: a practical usage guide. Biotechniques 50:98-115
Perry, Seth W; Barbieri, Justin; Tong, Ning et al. (2010) Human immunodeficiency virus-1 Tat activates calpain proteases via the ryanodine receptor to enhance surface dopamine transporter levels and increase transporter-specific uptake and Vmax. J Neurosci 30:14153-64

Showing the most recent 10 out of 38 publications