Abstract

EXCEED THE SPACE PROVIDED. PERFORMANCE SITE(S) (organization, city, state) Anatomy and Neurobiology University of California at Irvine Room 114,140 Irvine Hall Irvine, CA 92717-1280 KEY PERSONNEL. See instructions on Page Name Ji-Ying Sze Shenyuan Zhang Anahid E. Powell Kai-Xuan Shi To be named 11. Use continuation pages as needed to provide the required information in the format shown below. Organization Role on Project DC Irvine Principal Investigator DC Irvine Graduate Student DC Irvine Graduate Student DC Irvine Research Assistant UC Irvine Postdoctoral Fellow PHS 398(Rev. 4/98) Page 2 B B Number pages consecutively at the bottom throughout the application. Do not use suffixes such as 3a, 3b. ========================================Section End===========================================

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH064747-04
Application #
6919888
Study Section
Molecular, Cellular and Developmental Neurosciences 2 (MDCN)
Program Officer
Sieber, Beth-Anne
Project Start
2002-08-01
Project End
2007-05-31
Budget Start
2005-06-01
Budget End
2006-05-31
Support Year
4
Fiscal Year
2005
Total Cost
$263,837
Indirect Cost

  Institution

Name
University of California Irvine
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
046705849
City
Irvine
State
CA
Country
United States
Zip Code
92697

  Publications

Xu, Lu; Choi, Sunju; Xie, Yusu et al. (2015) Cell-Autonomous G? Signaling Defines Neuron-Specific Steady State Serotonin Synthesis in Caenorhabditis elegans. PLoS Genet 11:e1005540
Xie, Yusu; Moussaif, Mustapha; Choi, Sunju et al. (2013) RFX transcription factor DAF-19 regulates 5-HT and innate immune responses to pathogenic bacteria in Caenorhabditis elegans. PLoS Genet 9:e1003324
Jafari, Gholamali; Xie, Yusu; Kullyev, Andrey et al. (2011) Regulation of extrasynaptic 5-HT by serotonin reuptake transporter function in 5-HT-absorbing neurons underscores adaptation behavior in Caenorhabditis elegans. J Neurosci 31:8948-57
Govorunova, Elena G; Moussaif, Mustapha; Kullyev, Andrey et al. (2010) A homolog of FHM2 is involved in modulation of excitatory neurotransmission by serotonin in C. elegans. PLoS One 5:e10368
Kullyev, Andrey; Dempsey, Catherine M; Miller, Sarah et al. (2010) A genetic survey of fluoxetine action on synaptic transmission in Caenorhabditis elegans. Genetics 186:929-41
Moussaif, Mustapha; Sze, Ji Ying (2009) Intraflagellar transport/Hedgehog-related signaling components couple sensory cilium morphology and serotonin biosynthesis in Caenorhabditis elegans. J Neurosci 29:4065-75
McLaughlin, Katie J; Gomez, Juan L; Baran, Sarah E et al. (2007) The effects of chronic stress on hippocampal morphology and function: an evaluation of chronic restraint paradigms. Brain Res 1161:56-64
Balamurugan, Krishnaswamy; Ashokkumar, Balasubramaniem; Moussaif, Mustapha et al. (2007) Cloning and functional characterization of a folate transporter from the nematode Caenorhabditis elegans. Am J Physiol Cell Physiol 293:C670-81