The purpose of this study is to determine an optimum lung hyperinflation volume that will produce minimal changes in mean arterial pressure (MAP) and prevent post-suctioning hypoxemia. The sample will consist of 50 male post-coronary artery bypass graft patients who are at least four hours post surgery and determined to be hemodynamically stable according to set criteria. The subjects will receive three consecutive lung hyperinflations at one of the four randomly ordered volumes (12cc/Kg, 14cc/Kg, 16cc/Kg, and 18cc/Kg of lean body weight) in 15 seconds via the Ma1 ventilator """"""""sigh"""""""" control at FI02 100% MAP will be monitored continuously. The lung hyperinflation will be immediately followed by suctioning with a 14FR catheter. Suction (200mmHg flow rate 16L/min) will be applied to the catheter continuously while rotating and withdrawing for 10 seconds. The three lung hyperinflations (at the set volume, followed by suctioning will be repeated x 3. Following the last suction pass, arterial blood gases will be withdrawn at time 0, 30, 60, 120, 180, and 300 seconds post-suctioning. The protocal will be repeated one hour later until all four folumes have tested. The results of this study will provide nurses with parameters for administering lung hyperinflation to critically ill patients.

Agency
National Institute of Health (NIH)
Institute
National Institute of Nursing Research (NINR)
Type
Research Project (R01)
Project #
5R01NR001160-03
Application #
3391152
Study Section
(SRC)
Project Start
1984-09-28
Project End
1988-03-27
Budget Start
1986-09-28
Budget End
1988-03-27
Support Year
3
Fiscal Year
1986
Total Cost
Indirect Cost
Name
Ohio State University
Department
Type
Schools of Nursing
DUNS #
098987217
City
Columbus
State
OH
Country
United States
Zip Code
43210
Stone, K S; Bell, S D; Preusser, B A (1991) The effect of repeated endotracheal suctioning on arterial blood pressure. Appl Nurs Res 4:152-8
Stone, K S; Preusser, B A; Groch, K F et al. (1991) The effect of lung hyperinflation and endotracheal suctioning on cardiopulmonary hemodynamics. Nurs Res 40:76-80
Stone, K S; Talaganis, S A; Preusser, B et al. (1991) Effect of lung hyperinflation and endotracheal suctioning on heart rate and rhythm in patients after coronary artery bypass graft surgery. Heart Lung 20:443-50
Stone, K S; Vorst, E C; Lanham, B et al. (1989) Effects of lung hyperinflation on mean arterial pressure and postsuctioning hypoxemia. Heart Lung 18:377-85