This research studies the judgments of women regarding estrogen replacement therapy (ERT) as they anticipate and experience menopause. The decision to take or not to take ERT is complex. While the use of ERT relieves hot flashes ad decreases the risk of osteoporosis, it may also increase the risk of endometrial cancer. The addition of progestin to the therapy reduces the risk of endometrial cancer while maintaining benefits, but causes a resumption of cyclic bleeding. Women need to be fully informed of risks, benefits and implications of ERT in order to make optimal decisions. This also requires an understanding of menopause and the options available for relief of symptoms. This study focuses on the judgments of premenopausal and menopausal women, judgments which ultimately lead to behavioral decisions.
The aim of this study is to identify and systematically assess the factors which impact on women's judgments about ERT (initial use of) for menopausal symptoms. It is hypothesized that the judgment is influenced by a woman's perceptions, experience and expectations of menopause, as well as other factors such as sociodemographic characteristics, previous health care behaviors and experiences, and knowledge of menopause. This study will identify the relation of these variables to the ERT judgment. A research method drawn from social judgment theory will be used to design written cases to study four factors: risk of osteoporosis, endometrial cancer, severity of menopausal symptoms, and use of progestin with resumption of cyclic bleeding. Multivariate analyses will be used on data from 200 women in order to define women's policies in using information to judge ERT. Written instruments will also assess women's sociodemographic characteristics and health behaviors, expectations or experience with menopausal symptoms, perceptions and knowledge of menopause. A cluster analysis will be used to identify groups with similar sets of rating policies. We will then use multiple discriminant analyses to determine sociodemographic and health correlates of ERT judgment strategies. Thinking aloud protocols done with a subsample of women from the largest clusters will complement the statistical analyses and assist with the interpretation of data. Findings from this study will contribute to understanding the experience of menopause and provide data for subsequently develop a nursing intervention to assist women to make informed decisions regarding ERT.

Agency
National Institute of Health (NIH)
Institute
National Institute of Nursing Research (NINR)
Type
Research Project (R01)
Project #
1R01NR001245-01A1
Application #
3391180
Study Section
(SRC)
Project Start
1986-09-25
Project End
1989-03-24
Budget Start
1986-09-25
Budget End
1987-09-24
Support Year
1
Fiscal Year
1986
Total Cost
Indirect Cost
Name
Michigan State University
Department
Type
Schools of Nursing
DUNS #
193247145
City
East Lansing
State
MI
Country
United States
Zip Code
48824
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Holmes-Rovner, M; Kroll, J; Rovner, D R et al. (1999) Patient decision support intervention: increased consistency with decision analytic models. Med Care 37:270-84
Rothert, M L; Holmes-Rovner, M; Rovner, D et al. (1997) An educational intervention as decision support for menopausal women. Res Nurs Health 20:377-87
Holmes-Rovner, M; Padonu, G; Kroll, J et al. (1996) African-American women's attitudes and expectations of menopause. Am J Prev Med 12:420-3
Rothert, M; Rovner, D; Holmes, M et al. (1990) Women's use of information regarding hormone replacement therapy. Res Nurs Health 13:355-66