Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS012745-18
Application #
2262474
Study Section
Experimental Therapeutics Subcommittee 1 (ET)
Project Start
1975-05-01
Project End
1998-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
18
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Evanston Hospital
Department
Type
DUNS #
City
Evanston
State
IL
Country
United States
Zip Code
60201

  Publications

Groothuis, Dennis R; Vavra, Michael W; Schlageter, Kurt E et al. (2007) Efflux of drugs and solutes from brain: the interactive roles of diffusional transcapillary transport, bulk flow and capillary transporters. J Cereb Blood Flow Metab 27:43-56
Ali, Mir J; Navalitloha, Yot; Vavra, Michael W et al. (2006) Isolation of drug delivery from drug effect: problems of optimizing drug delivery parameters. Neuro Oncol 8:109-18
Navalitloha, Yot; Schwartz, Erica S; Groothuis, Elizabeth N et al. (2006) Therapeutic implications of tumor interstitial fluid pressure in subcutaneous RG-2 tumors. Neuro Oncol 8:227-33
Vavra, Michael; Ali, M Jaffer; Kang, Eric W-Y et al. (2004) Comparative pharmacokinetics of 14C-sucrose in RG-2 rat gliomas after intravenous and convection-enhanced delivery. Neuro Oncol 6:104-12
Groothuis, D R (2000) The blood-brain and blood-tumor barriers: a review of strategies for increasing drug delivery. Neuro Oncol 2:45-59
Groothuis, D R; Benalcazar, H; Allen, C V et al. (2000) Comparison of cytosine arabinoside delivery to rat brain by intravenous, intrathecal, intraventricular and intraparenchymal routes of administration. Brain Res 856:281-90
Schlageter, K E; Molnar, P; Lapin, G D et al. (1999) Microvessel organization and structure in experimental brain tumors: microvessel populations with distinctive structural and functional properties. Microvasc Res 58:312-28
Molnar, P P; O'Neill, B P; Scheithauer, B W et al. (1999) The blood-brain barrier in primary CNS lymphomas: ultrastructural evidence of endothelial cell death. Neuro Oncol 1:89-100
Groothuis, D R; Ward, S; Itskovich, A C et al. (1999) Comparison of 14C-sucrose delivery to the brain by intravenous, intraventricular, and convection-enhanced intracerebral infusion. J Neurosurg 90:321-31
Molnar, P; Fekete, I; Schlageter, K E et al. (1999) Absence of host-site influence on angiogenesis, blood flow, and permeability in transplanted RG-2 gliomas. Drug Metab Dispos 27:1085-91

Showing the most recent 10 out of 38 publications