Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
2R01NS013560-20A1
Application #
2262556
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Project Start
1978-07-01
Project End
2001-05-31
Budget Start
1996-07-01
Budget End
1997-05-31
Support Year
20
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of California Santa Barbara
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
City
Santa Barbara
State
CA
Country
United States
Zip Code
93106

  Publications

Choi, Myung Chul; Chung, Peter J; Song, Chaeyeon et al. (2017) Paclitaxel suppresses Tau-mediated microtubule bundling in a concentration-dependent manner. Biochim Biophys Acta Gen Subj 1861:3456-3463
Chung, Peter J; Song, Chaeyeon; Deek, Joanna et al. (2016) Tau mediates microtubule bundle architectures mimicking fascicles of microtubules found in the axon initial segment. Nat Commun 7:12278
Chung, Peter J; Choi, Myung Chul; Miller, Herbert P et al. (2015) Direct force measurements reveal that protein Tau confers short-range attractions and isoform-dependent steric stabilization to microtubules. Proc Natl Acad Sci U S A 112:E6416-25
Ojeda-Lopez, Miguel A; Needleman, Daniel J; Song, Chaeyeon et al. (2014) Transformation of taxol-stabilized microtubules into inverted tubulin tubules triggered by a tubulin conformation switch. Nat Mater 13:195-203
Needleman, Daniel J; Ojeda-Lopez, Miguel A; Raviv, Uri et al. (2013) Ion specific effects in bundling and depolymerization of taxol-stabilized microtubules. Faraday Discuss 166:31-45
Lopus, Manu; Manatschal, Cristina; Buey, Ruben M et al. (2012) Cooperative stabilization of microtubule dynamics by EB1 and CLIP-170 involves displacement of stably bound P(i) at microtubule ends. Biochemistry 51:3021-30
Lopus, Manu (2011) Antibody-DM1 conjugates as cancer therapeutics. Cancer Lett 307:113-8
Davé, Rahul H; Saengsawang, Witchuda; Lopus, Manu et al. (2011) A molecular and structural mechanism for G protein-mediated microtubule destabilization. J Biol Chem 286:4319-28
Safinya, Cyrus R; Raviv, Uri; Needleman, Daniel J et al. (2011) Nanoscale assembly in biological systems: from neuronal cytoskeletal proteins to curvature stabilizing lipids. Adv Mater 23:2260-70
Kiris, Erkan; Ventimiglia, Donovan; Sargin, Mehmet E et al. (2011) Combinatorial Tau pseudophosphorylation: markedly different regulatory effects on microtubule assembly and dynamic instability than the sum of the individual parts. J Biol Chem 286:14257-70

Showing the most recent 10 out of 100 publications