Focal microwave-induced hyperthermia is being studied in an attempt to evaluate its utility in the management of glioblastoma multiforme. Studies consist of a) neuroradiobiological assays of thresholds of damage to normal brain following focal heating, b) dosimetric evaluation of heating efficacy, and c) engineering developments to improve the delivery and controllability of microwave-induced hyperthermia. Two methods of heating are being employed - one invasive and one non-invasive.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS016316-06
Application #
3396813
Study Section
Radiation Study Section (RAD)
Project Start
1979-09-24
Project End
1986-12-31
Budget Start
1985-04-01
Budget End
1986-12-31
Support Year
6
Fiscal Year
1985
Total Cost
Indirect Cost
Name
University of Maryland Baltimore
Department
Type
Schools of Medicine
DUNS #
003255213
City
Baltimore
State
MD
Country
United States
Zip Code
21201
Samaras, G M; Eddy, H A; Better, W E et al. (1986) The use of swine in brain interstitial radiation studies. Lab Anim Sci 36:381-5