Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS017928-15
Application #
2263308
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Program Officer
Baughman, Robert W
Project Start
1981-12-01
Project End
1997-11-30
Budget Start
1995-12-01
Budget End
1997-11-30
Support Year
15
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Physiology
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Bendahhou, S; Cummins, T R; Agnew, W S (1997) Mechanism of modulation of the voltage-gated skeletal and cardiac muscle sodium channels by fatty acids. Am J Physiol 272:C592-600
Bendahhou, S; Agnew, W S (1996) Enhancement of the Shaker B delta6-46 current by fatty acids depends on the activation of the lipoxygenase metabolic pathway. Pflugers Arch 432:1091-3
Bendahhou, S; Cummins, T R; Potts, J F et al. (1995) Serine-1321-independent regulation of the mu 1 adult skeletal muscle Na+ channel by protein kinase C. Proc Natl Acad Sci U S A 92:12003-7
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Potts, J F; Regan, M R; Rochelle, J M et al. (1993) A glial-specific voltage-sensitive Na channel gene maps close to clustered genes for neuronal isoforms on mouse chromosome 2. Biochem Biophys Res Commun 197:100-4
Tong, J; Potts, J F; Rochelle, J M et al. (1993) A single B1 subunit mapped to mouse chromosome 7 may be a common component of Na channel isoforms from brain, skeletal muscle and heart. Biochem Biophys Res Commun 195:679-85
Emerick, M C; Shenkel, S; Agnew, W S (1993) Regulation of the eel electroplax Na channel and phosphorylation of residues on amino- and carboxyl-terminal domains by cAMP-dependent protein kinase. Biochemistry 32:9435-44
Ukomadu, C; Zhou, J; Sigworth, F J et al. (1992) muI Na+ channels expressed transiently in human embryonic kidney cells: biochemical and biophysical properties. Neuron 8:663-76
Hingorani, S R; Agnew, W S (1991) A rapid ion-exchange assay for detergent-solubilized inositol 1,4,5-trisphosphate receptors. Anal Biochem 194:204-13
Trimmer, J S (1991) Immunological identification and characterization of a delayed rectifier K+ channel polypeptide in rat brain. Proc Natl Acad Sci U S A 88:10764-8

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