Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
2R01NS018596-13A1
Application #
2263440
Study Section
Experimental Virology Study Section (EVR)
Project Start
1996-02-01
Project End
2000-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
13
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Microbiology/Immun/Virology
Type
Schools of Public Health
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Baxter, Victoria K; Glowinski, Rebecca; Braxton, Alicia M et al. (2017) Glutamine antagonist-mediated immune suppression decreases pathology but delays virus clearance in mice during nonfatal alphavirus encephalomyelitis. Virology 508:134-149
Griffin, Diane E (2010) Emergence and re-emergence of viral diseases of the central nervous system. Prog Neurobiol 91:95-101
Park, Eunhye; Griffin, Diane E (2009) The nsP3 macro domain is important for Sindbis virus replication in neurons and neurovirulence in mice. Virology 388:305-14
Park, Eunhye; Griffin, Diane E (2009) Interaction of Sindbis virus non-structural protein 3 with poly(ADP-ribose) polymerase 1 in neuronal cells. J Gen Virol 90:2073-80
Knight, Ronald L; Schultz, Kimberly L W; Kent, Rebekah J et al. (2009) Role of N-linked glycosylation for sindbis virus infection and replication in vertebrate and invertebrate systems. J Virol 83:5640-7
Ng, Ching G; Coppens, Isabelle; Govindarajan, Dhanasekaran et al. (2008) Effect of host cell lipid metabolism on alphavirus replication, virion morphogenesis, and infectivity. Proc Natl Acad Sci U S A 105:16326-31
Ng, Ching G; Griffin, Diane E (2006) Acid sphingomyelinase deficiency increases susceptibility to fatal alphavirus encephalomyelitis. J Virol 80:10989-99
Bear, J Steven; Byrnes, Andrew P; Griffin, Diane E (2006) Heparin-binding and patterns of virulence for two recombinant strains of Sindbis virus. Virology 347:183-90
Vernon, Patty S; Griffin, Diane E (2005) Characterization of an in vitro model of alphavirus infection of immature and mature neurons. J Virol 79:3438-47
Zaitseva, Elena; Mittal, Aditya; Griffin, Diane E et al. (2005) Class II fusion protein of alphaviruses drives membrane fusion through the same pathway as class I proteins. J Cell Biol 169:167-77

Showing the most recent 10 out of 55 publications