Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
3R01NS020181-08S1
Application #
3400401
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Project Start
1983-12-01
Project End
1995-03-31
Budget Start
1992-04-01
Budget End
1993-03-31
Support Year
8
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Tufts University
Department
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02111
Schein, J C; Wang, J K T; Roffler-Tarlov, S K (2005) The effect of GIRK2(wv) on neurite growth, protein expression, and viability in the CNS-derived neuronal cell line, CATH.A-differentiated. Neuroscience 134:21-32
Peng, Jun; Wu, Zhijin; Wu, Yongqin et al. (2002) Inhibition of caspases protects cerebellar granule cells of the weaver mouse from apoptosis and improves behavioral phenotype. J Biol Chem 277:44285-91
Schimmel, J J; Crews, L; Roffler-Tarlov, S et al. (1999) 4.5 kb of the rat tyrosine hydroxylase 5' flanking sequence directs tissue specific expression during development and contains consensus sites for multiple transcription factors. Brain Res Mol Brain Res 74:1-14
Schein, J C; Hunter, D D; Roffler-Tarlov, S (1998) Girk2 expression in the ventral midbrain, cerebellum, and olfactory bulb and its relationship to the murine mutation weaver. Dev Biol 204:432-50
Harrison, S M; Roffler-Tarlov, S K (1998) Cell death during development of testis and cerebellum in the mutant mouse weaver. Dev Biol 195:174-86
Roffler-Tarlov, S; Brown, J J; Tarlov, E et al. (1996) Programmed cell death in the absence of c-Fos and c-Jun. Development 122:1-9
Oo, T F; Blazeski, R; Harrison, S M et al. (1996) Neuron death in the substantia nigra of weaver mouse occurs late in development and is not apoptotic. J Neurosci 16:6134-45
Roffler-Tarlov, S; Martin, B; Graybiel, A M et al. (1996) Cell death in the midbrain of the murine mutation weaver. J Neurosci 16:1819-26
Banerjee, S A; Roffler-Tarlov, S; Szabo, M et al. (1994) DNA regulatory sequences of the rat tyrosine hydroxylase gene direct correct catecholaminergic cell-type specificity of a human growth hormone reporter in the CNS of transgenic mice causing a dwarf phenotype. Brain Res Mol Brain Res 24:89-106
Grosson, C L; MacDonald, M E; Duyao, M P et al. (1994) Synteny conservation of the Huntington's disease gene and surrounding loci on mouse Chromosome 5. Mamm Genome 5:424-8

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