Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS021328-03
Application #
3402370
Study Section
Mammalian Genetics Study Section (MGN)
Project Start
1984-09-01
Project End
1987-08-31
Budget Start
1986-09-01
Budget End
1987-08-31
Support Year
3
Fiscal Year
1986
Total Cost
Indirect Cost
Name
Emory University
Department
Type
Schools of Medicine
DUNS #
042250712
City
Atlanta
State
GA
Country
United States
Zip Code
30322
Singh, Larry N; Crowston, Jonathan G; Lopez Sanchez, M Isabel G et al. (2018) Mitochondrial DNA Variation and Disease Susceptibility in Primary Open-Angle Glaucoma. Invest Ophthalmol Vis Sci 59:4598-4602
Pei, Liming; Wallace, Douglas C (2018) Mitochondrial Etiology of Neuropsychiatric Disorders. Biol Psychiatry 83:722-730
Ortiz-González, Xilma R; Tintos-Hernández, Jesus A; Keller, Kierstin et al. (2018) Homozygous boricua TBCK mutation causes neurodegeneration and aberrant autophagy. Ann Neurol 83:153-165
Weisz, Eliana D; Towheed, Atif; Monyak, Rachel E et al. (2018) Loss of Drosophila FMRP leads to alterations in energy metabolism and mitochondrial function. Hum Mol Genet 27:95-106
Kandel, Judith; Picard, Martin; Wallace, Douglas C et al. (2017) Mitochondrial DNA 3243A>G heteroplasmy is associated with changes in cytoskeletal protein expression and cell mechanics. J R Soc Interface 14:
Kim, Chul; Potluri, Prasanth; Khalil, Ahmed et al. (2017) An X-chromosome linked mouse model (Ndufa1S55A) for systemic partial Complex I deficiency for studying predisposition to neurodegeneration and other diseases. Neurochem Int 109:78-93
Morrow, Ryan M; Picard, Martin; Derbeneva, Olga et al. (2017) Mitochondrial energy deficiency leads to hyperproliferation of skeletal muscle mitochondria and enhanced insulin sensitivity. Proc Natl Acad Sci U S A 114:2705-2710
Sonney, Sanjay; Leipzig, Jeremy; Lott, Marie T et al. (2017) Predicting the pathogenicity of novel variants in mitochondrial tRNA with MitoTIP. PLoS Comput Biol 13:e1005867
Wallace, Douglas C (2017) A Mitochondrial Etiology of Neuropsychiatric Disorders. JAMA Psychiatry 74:863-864
Coskun, Pinar; Helguera, Pablo; Nemati, Zahra et al. (2017) Metabolic and Growth Rate Alterations in Lymphoblastic Cell Lines Discriminate Between Down Syndrome and Alzheimer's Disease. J Alzheimers Dis 55:737-748

Showing the most recent 10 out of 210 publications