Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS023868-10
Application #
2264967
Study Section
Neurology B Subcommittee 2 (NEUB)
Project Start
1986-07-01
Project End
1999-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas Sw Medical Center Dallas
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
City
Dallas
State
TX
Country
United States
Zip Code
75390
Sama, Reddy Ranjith K; Fallini, Claudia; Gatto, Rodolfo et al. (2017) ALS-linked FUS exerts a gain of toxic function involving aberrant p38 MAPK activation. Sci Rep 7:115
Leo, Lanfranco; Weissmann, Carina; Burns, Matthew et al. (2017) Mutant spastin proteins promote deficits in axonal transport through an isoform-specific mechanism involving casein kinase 2 activation. Hum Mol Genet 26:2321-2334
Brady, Scott T; Morfini, Gerardo A (2017) Regulation of motor proteins, axonal transport deficits and adult-onset neurodegenerative diseases. Neurobiol Dis 105:273-282
Moreno, H; Morfini, G; Buitrago, L et al. (2016) Tau pathology-mediated presynaptic dysfunction. Neuroscience 325:30-8
Tiernan, Chelsea T; Combs, Benjamin; Cox, Kristine et al. (2016) Pseudophosphorylation of tau at S422 enhances SDS-stable dimer formation and impairs both anterograde and retrograde fast axonal transport. Exp Neurol 283:318-29
Song, Yuyu; Kang, Minsu; Morfini, Gerardo et al. (2016) Fast axonal transport in isolated axoplasm from the squid giant axon. Methods Cell Biol 131:331-48
Kang, Minsu; Baker, Lisa; Song, Yuyu et al. (2016) Biochemical analysis of axon-specific phosphorylation events using isolated squid axoplasms. Methods Cell Biol 131:199-216
Berth, Sarah; Caicedo, Hector Hugo; Sarma, Tulika et al. (2015) Internalization and axonal transport of the HIV glycoprotein gp120. ASN Neuro 7:
Gatto, Rodolfo G; Chu, Yaping; Ye, Allen Q et al. (2015) Analysis of YFP(J16)-R6/2 reporter mice and postmortem brains reveals early pathology and increased vulnerability of callosal axons in Huntington's disease. Hum Mol Genet 24:5285-98
Song, Yuyu; Brady, Scott T (2015) Post-translational modifications of tubulin: pathways to functional diversity of microtubules. Trends Cell Biol 25:125-36

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