Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
2R01NS023885-09A2
Application #
2264986
Study Section
Physiology Study Section (PHY)
Project Start
1986-07-01
Project End
2000-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Allegheny University of Health Sciences
Department
Physiology
Type
Schools of Medicine
DUNS #
City
Philadelphia
State
PA
Country
United States
Zip Code
19129
Yan, Dong; White, Michael M (2002) Interaction of d-tubocurarine analogs with mutant 5-HT(3) receptors. Neuropharmacology 43:367-73
Chen, Z; White, M M (2000) Forskolin modulates acetylcholine receptor gating by interacting with the small extracellular loop between the M2 and M3 transmembrane domains. Cell Mol Neurobiol 20:569-77
Kosolapov, A V; Filatov, G N; White, M M (2000) Acetylcholine receptor gating is influenced by the polarity of amino acids at position 9' in the M2 domain. J Membr Biol 174:191-7
Yan, D; Schulte, M K; Bloom, K E et al. (1999) Structural features of the ligand-binding domain of the serotonin 5HT3 receptor. J Biol Chem 274:5537-41
Yan, D; Pedersen, S E; White, M M (1998) Interaction of D-tubocurarine analogs with the 5HT3 receptor. Neuropharmacology 37:251-7
Filatov, G N; White, M M (1995) The role of conserved leucines in the M2 domain of the acetylcholine receptor in channel gating. Mol Pharmacol 48:379-84
Aylwin, M L; White, M M (1994) Ligand-receptor interactions in the nicotinic acetylcholine receptor probed using multiple substitutions at conserved tyrosines on the alpha subunit. FEBS Lett 349:99-103
Aylwin, M L; White, M M (1994) Gating properties of mutant acetylcholine receptors. Mol Pharmacol 46:1149-55
O'Leary, M E; Filatov, G N; White, M M (1994) Characterization of d-tubocurarine binding site of Torpedo acetylcholine receptor. Am J Physiol 266:C648-53
Filatov, G N; Aylwin, M L; White, M M (1993) Selective enhancement of the interaction of curare with the nicotinic acetylcholine receptor. Mol Pharmacol 44:237-41

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