Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
1R01NS025296-01
Application #
3410553
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Project Start
1987-07-01
Project End
1990-06-30
Budget Start
1987-07-01
Budget End
1988-06-30
Support Year
1
Fiscal Year
1987
Total Cost
Indirect Cost
Name
University of Maryland Baltimore
Department
Type
Schools of Medicine
DUNS #
003255213
City
Baltimore
State
MD
Country
United States
Zip Code
21201
Alkondon, Manickavasagom; Pereira, Edna F R; Todd, Spencer W et al. (2015) Functional G-protein-coupled receptor 35 is expressed by neurons in the CA1 field of the hippocampus. Biochem Pharmacol 93:506-18
Banerjee, Jyotirmoy; Alkondon, Manickavasagom; Albuquerque, Edson X et al. (2013) Contribution of CA3 and CA1 pyramidal neurons to the tonic *7 nAChR-dependent glutamatergic input to CA1 pyramidal neurons. Neurosci Lett 554:167-71
Albuquerque, Edson X; Schwarcz, Robert (2013) Kynurenic acid as an antagonist of ýý7 nicotinic acetylcholine receptors in the brain: facts and challenges. Biochem Pharmacol 85:1027-32
Banerjee, Jyotirmoy; Alkondon, Manickavasagom; Pereira, Edna F R et al. (2012) Regulation of GABAergic inputs to CA1 pyramidal neurons by nicotinic receptors and kynurenic acid. J Pharmacol Exp Ther 341:500-9
Wang, Xiao-Dan; Notarangelo, Francesca M; Wang, Ji-Zuo et al. (2012) Kynurenic acid and 3-hydroxykynurenine production from D-kynurenine in mice. Brain Res 1455:1-9
Notarangelo, Francesca M; Wu, Hui-Qiu; Macherone, Anthony et al. (2012) Gas chromatography/tandem mass spectrometry detection of extracellular kynurenine and related metabolites in normal and lesioned rat brain. Anal Biochem 421:573-81
Pocivavsek, Ana; Wu, Hui-Qiu; Elmer, Greg I et al. (2012) Pre- and postnatal exposure to kynurenine causes cognitive deficits in adulthood. Eur J Neurosci 35:1605-12
Banerjee, Jyotirmoy; Alkondon, Manickavasagom; Albuquerque, Edson X (2012) Kynurenic acid inhibits glutamatergic transmission to CA1 pyramidal neurons via ?7 nAChR-dependent and -independent mechanisms. Biochem Pharmacol 84:1078-87
Pocivavsek, Ana; Wu, Hui-Qiu; Potter, Michelle C et al. (2011) Fluctuations in endogenous kynurenic acid control hippocampal glutamate and memory. Neuropsychopharmacology 36:2357-67
Alkondon, Manickavasagom; Pereira, Edna F R; Albuquerque, Edson X (2011) Endogenous activation of nAChRs and NMDA receptors contributes to the excitability of CA1 stratum radiatum interneurons in rat hippocampal slices: effects of kynurenic acid. Biochem Pharmacol 82:842-51

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