Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS025304-10
Application #
2265522
Study Section
Neurology C Study Section (NEUC)
Project Start
1987-07-01
Project End
2000-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Cleveland Clinic Lerner
Department
Type
DUNS #
017730458
City
Cleveland
State
OH
Country
United States
Zip Code
44195

  Publications

Liu, Yiting; Given, Katherine S; Owens, Gregory P et al. (2018) Distinct patterns of glia repair and remyelination in antibody-mediated demyelination models of multiple sclerosis and neuromyelitis optica. Glia 66:2575-2588
Liu, Yiting; Harlow, Danielle E; Given, Katherine S et al. (2016) Variable sensitivity to complement-dependent cytotoxicity in murine models of neuromyelitis optica. J Neuroinflammation 13:301
Harlow, Danielle E; Saul, Katherine E; Komuro, Hitoshi et al. (2015) Myelin Proteolipid Protein Complexes with ?v Integrin and AMPA Receptors In Vivo and Regulates AMPA-Dependent Oligodendrocyte Progenitor Cell Migration through the Modulation of Cell-Surface GluR2 Expression. J Neurosci 35:12018-32
Chen, Lu; Coleman, Ronald; Leang, Ronika et al. (2014) Human neural precursor cells promote neurologic recovery in a viral model of multiple sclerosis. Stem Cell Reports 2:825-37
Harlow, Danielle E; Macklin, Wendy B (2014) Inhibitors of myelination: ECM changes, CSPGs and PTPs. Exp Neurol 251:39-46
Greenberg, Milton L; Weinger, Jason G; Matheu, Melanie P et al. (2014) Two-photon imaging of remyelination of spinal cord axons by engrafted neural precursor cells in a viral model of multiple sclerosis. Proc Natl Acad Sci U S A 111:E2349-55
Harlow, Danielle E; Saul, Katherine E; Culp, Cecilia M et al. (2014) Expression of proteolipid protein gene in spinal cord stem cells and early oligodendrocyte progenitor cells is dispensable for normal cell migration and myelination. J Neurosci 34:1333-43
Hussain, Rashad; Ghoumari, Abdel M; Bielecki, Bartosz et al. (2013) The neural androgen receptor: a therapeutic target for myelin repair in chronic demyelination. Brain 136:132-46
Hu, Xiangyou; Schlanger, Rita; He, Wanxia et al. (2013) Reversing hypomyelination in BACE1-null mice with Akt-DD overexpression. FASEB J 27:1868-73
Inamura, Naoko; Sugio, Shouta; Macklin, Wendy B et al. (2012) Gene induction in mature oligodendrocytes with a PLP-tTA mouse line. Genesis 50:424-8

Showing the most recent 10 out of 47 publications