Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
7R01NS025655-02
Application #
3410986
Study Section
Neurology A Study Section (NEUA)
Project Start
1989-02-01
Project End
1992-01-31
Budget Start
1989-02-01
Budget End
1990-01-31
Support Year
2
Fiscal Year
1988
Total Cost
Indirect Cost
Name
University of Illinois at Chicago
Department
Type
Schools of Medicine
DUNS #
121911077
City
Chicago
State
IL
Country
United States
Zip Code
60612
Emborg, M E; Ma, S Y; Mufson, E J et al. (1998) Age-related declines in nigral neuronal function correlate with motor impairments in rhesus monkeys. J Comp Neurol 401:253-65
Kordower, J H; Mufson, E J; Fox, N et al. (1997) Cellular delivery of NGF does not alter the expression of beta-amyloid immunoreactivity in young or aged nonhuman primates. Exp Neurol 145:586-91
Kordower, J H; Chen, E Y; Mufson, E J et al. (1996) Intrastriatal implants of polymer encapsulated cells genetically modified to secrete human nerve growth factor: trophic effects upon cholinergic and noncholinergic striatal neurons. Neuroscience 72:63-77
Emerich, D F; Winn, S R; Harper, J et al. (1994) Implants of polymer-encapsulated human NGF-secreting cells in the nonhuman primate: rescue and sprouting of degenerating cholinergic basal forebrain neurons. J Comp Neurol 349:148-64
Burke, M A; Mobley, W C; Cho, J et al. (1994) Loss of developing cholinergic basal forebrain neurons following excitotoxic lesions of the hippocampus: rescue by neurotrophins. Exp Neurol 130:178-95
Kordower, J H; Chen, E Y; Sladek Jr, J R et al. (1994) trk-immunoreactivity in the monkey central nervous system: forebrain. J Comp Neurol 349:20-35
Mufson, E J; Higgins, G A; Kordower, J H (1991) Nerve growth factor receptor immunoreactivity in the new world monkey (Cebus apella) and human cerebellum. J Comp Neurol 308:555-75
Mufson, E J; Presley, L N; Kordower, J H (1991) Nerve growth factor receptor immunoreactivity within the nucleus basalis (Ch4) in Parkinson's disease: reduced cell numbers and co-localization with cholinergic neurons. Brain Res 539:19-30
Hansen, J T; Fiandaca, M S; Kordower, J H et al. (1990) Striatal adrenal medulla/sural nerve cografts in hemiparkinsonian monkeys. Prog Brain Res 82:573-80
Kordower, J H; Fiandaca, M S (1990) Response of the monkey cholinergic septohippocampal system to fornix transection: a histochemical and cytochemical analysis. J Comp Neurol 298:443-57

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