Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS026920-08
Application #
2266201
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Project Start
1988-12-01
Project End
1997-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Washington
Department
Pharmacology
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Maison, Stéphane F; Liu, Xiao-Ping; Vetter, Douglas E et al. (2010) Muscarinic signaling in the cochlea: presynaptic and postsynaptic effects on efferent feedback and afferent excitability. J Neurosci 30:6751-62
Nathanson, Neil M (2008) Synthesis, trafficking, and localization of muscarinic acetylcholine receptors. Pharmacol Ther 119:33-43
Chmelar, Renee S; Nathanson, Neil M (2006) Identification of a novel apical sorting motif and mechanism of targeting of the M2 muscarinic acetylcholine receptor. J Biol Chem 281:35381-96
Zhang, Yunfeng; Hamilton, Susan E; Nathanson, Neil M et al. (2006) Decreased input-specific plasticity of the auditory cortex in mice lacking M1 muscarinic acetylcholine receptors. Cereb Cortex 16:1258-65
Laszlo, George S; Rosoff, Marc L; Amieux, Paul S et al. (2006) Multiple promoter elements required for leukemia inhibitory factor-stimulated M2 muscarinic acetylcholine receptor promoter activity. J Neurochem 98:1302-15
Goin, Juan C; Nathanson, Neil M (2006) Quantitative analysis of muscarinic acetylcholine receptor homo- and heterodimerization in live cells: regulation of receptor down-regulation by heterodimerization. J Biol Chem 281:5416-25
Zhang, Yunfeng; Dyck, Richard H; Hamilton, Susan E et al. (2005) Disrupted tonotopy of the auditory cortex in mice lacking M1 muscarinic acetylcholine receptor. Hear Res 201:145-55
Iverson, Heidi A; Fox 3rd, David; Nadler, Laurie S et al. (2005) Identification and structural determination of the M(3) muscarinic acetylcholine receptor basolateral sorting signal. J Biol Chem 280:24568-75
Shen, Weixing; Hamilton, Susan E; Nathanson, Neil M et al. (2005) Cholinergic suppression of KCNQ channel currents enhances excitability of striatal medium spiny neurons. J Neurosci 25:7449-58
Anagnostaras, Stephan G; Murphy, Geoffrey G; Hamilton, Susan E et al. (2003) Selective cognitive dysfunction in acetylcholine M1 muscarinic receptor mutant mice. Nat Neurosci 6:51-8

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