Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS028562-06
Application #
2267007
Study Section
Physical Biochemistry Study Section (PB)
Project Start
1990-04-01
Project End
1997-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Carnegie-Mellon University
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
052184116
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Hackney, David D; Baek, Nahyeon; Snyder, Avin C (2009) Half-site inhibition of dimeric kinesin head domains by monomeric tail domains. Biochemistry 48:3448-56
Browning, Heidi; Hackney, David D (2005) The EB1 homolog Mal3 stimulates the ATPase of the kinesin Tea2 by recruiting it to the microtubule. J Biol Chem 280:12299-304
Hackney, David D (2005) The tethered motor domain of a kinesin-microtubule complex catalyzes reversible synthesis of bound ATP. Proc Natl Acad Sci U S A 102:18338-43
Hackney, David D; Stock, Maryanne F; Moore, Jodi et al. (2003) Modulation of kinesin half-site ADP release and kinetic processivity by a spacer between the head groups. Biochemistry 42:12011-8
Stock, Maryanne F; Chu, Jessica; Hackney, David D (2003) The kinesin family member BimC contains a second microtubule binding region attached to the N terminus of the motor domain. J Biol Chem 278:52315-22
Browning, Heidi; Hackney, David D; Nurse, Paul (2003) Targeted movement of cell end factors in fission yeast. Nat Cell Biol 5:812-8
DeBonis, Salvatore; Simorre, Jean-Pierre; Crevel, Isabelle et al. (2003) Interaction of the mitotic inhibitor monastrol with human kinesin Eg5. Biochemistry 42:338-49
Hackney, David D (2002) Pathway of ADP-stimulated ADP release and dissociation of tethered kinesin from microtubules. Implications for the extent of processivity. Biochemistry 41:4437-46
Hackney, D D; Jiang, W (2001) Assays for kinesin microtubule-stimulated ATPase activity. Methods Mol Biol 164:65-71
Stock, M F; Hackney, D D (2001) Expression of kinesin in Escherichia coli. Methods Mol Biol 164:43-8

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