Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS028721-07
Application #
2267124
Study Section
Pathology A Study Section (PTHA)
Project Start
1990-07-15
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Tennessee Health Science Center
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
941884009
City
Memphis
State
TN
Country
United States
Zip Code
38163
Dragatsis, I; Dietrich, P; Ren, H et al. (2018) Effect of early embryonic deletion of huntingtin from pyramidal neurons on the development and long-term survival of neurons in cerebral cortex and striatum. Neurobiol Dis 111:102-117
Reiner, Anton; Deng, Yun-Ping (2018) Disrupted striatal neuron inputs and outputs in Huntington's disease. CNS Neurosci Ther 24:250-280
Deng, Yun-Ping; Reiner, Anton (2016) Cholinergic interneurons in the Q140 knockin mouse model of Huntington's disease: Reductions in dendritic branching and thalamostriatal input. J Comp Neurol 524:3518-3529
Bruce, Laura L; Erichsen, Jonathan T; Reiner, Anton (2016) Neurochemical compartmentalization within the pigeon basal ganglia. J Chem Neuroanat 78:65-86
Reiner, Anton; Shelby, Evan; Wang, Hongbing et al. (2013) Striatal parvalbuminergic neurons are lost in Huntington's disease: implications for dystonia. Mov Disord 28:1691-9
Lei, Wanlong; Deng, Yunping; Liu, Bingbing et al. (2013) Confocal laser scanning microscopy and ultrastructural study of VGLUT2 thalamic input to striatal projection neurons in rats. J Comp Neurol 521:1354-77
Reiner, A; Wang, H B; Del Mar, N et al. (2012) BDNF may play a differential role in the protective effect of the mGluR2/3 agonist LY379268 on striatal projection neurons in R6/2 Huntington's disease mice. Brain Res 1473:161-72
Reiner, A; Lafferty, D C; Wang, H B et al. (2012) The group 2 metabotropic glutamate receptor agonist LY379268 rescues neuronal, neurochemical and motor abnormalities in R6/2 Huntington's disease mice. Neurobiol Dis 47:75-91
Reiner, Anton; Dragatsis, Ioannis; Dietrich, Paula (2011) Genetics and neuropathology of Huntington's disease. Int Rev Neurobiol 98:325-72
Mu, Shuhua; OuYang, Lisi; Liu, Bingbing et al. (2011) Preferential interneuron survival in the transition zone of 3-NP-induced striatal injury in rats. J Neurosci Res 89:744-54

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