Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
2R01NS029173-05A1
Application #
2267429
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Project Start
1991-08-01
Project End
2000-07-31
Budget Start
1996-09-15
Budget End
1997-07-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Colorado Denver
Department
Pharmacology
Type
Schools of Medicine
DUNS #
065391526
City
Aurora
State
CO
Country
United States
Zip Code
80045
Hoffman, Alexander F; Laaris, Nora; Kawamura, Masahito et al. (2010) Control of cannabinoid CB1 receptor function on glutamate axon terminals by endogenous adenosine acting at A1 receptors. J Neurosci 30:545-55
Masino, S A; Kawamura, M; Wasser, C D et al. (2009) Adenosine, ketogenic diet and epilepsy: the emerging therapeutic relationship between metabolism and brain activity. Curr Neuropharmacol 7:257-68
Dulla, Chris G; Frenguelli, Bruno G; Staley, Kevin J et al. (2009) Intracellular acidification causes adenosine release during states of hyperexcitability in the hippocampus. J Neurophysiol 102:1984-93
Masino, Susan A; Geiger, Jonathan D (2009) The ketogenic diet and epilepsy: is adenosine the missing link? Epilepsia 50:332-3
Masino, Susan A; Geiger, Jonathan D (2008) Are purines mediators of the anticonvulsant/neuroprotective effects of ketogenic diets? Trends Neurosci 31:273-8
Koranda, Jessica L; Masino, Susan A; Blaise, J Harry (2008) Bidirectional synaptic plasticity in the dentate gyrus of the awake freely behaving mouse. J Neurosci Methods 167:160-6
Gimenez-Llort, Lydia; Masino, Susan A; Diao, Lihong et al. (2005) Mice lacking the adenosine A1 receptor have normal spatial learning and plasticity in the CA1 region of the hippocampus, but they habituate more slowly. Synapse 57:8-16
Dulla, Chris G; Dobelis, Peter; Pearson, Tim et al. (2005) Adenosine and ATP link PCO2 to cortical excitability via pH. Neuron 48:1011-23
Masino, Susan A (2003) Quantitative comparison between functional imaging and single-unit spiking in rat somatosensory cortex. J Neurophysiol 89:1702-12
Masino, Susan A; Diao, Lihong; Illes, Peter et al. (2002) Modulation of hippocampal glutamatergic transmission by ATP is dependent on adenosine a(1) receptors. J Pharmacol Exp Ther 303:356-63

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