Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
3R01NS034914-05A1S1
Application #
6692304
Study Section
Special Emphasis Panel (ZRG1)
Program Officer
Oliver, Eugene J
Project Start
1995-09-30
Project End
2007-03-31
Budget Start
2002-04-15
Budget End
2003-03-31
Support Year
5
Fiscal Year
2003
Total Cost
$27,028
Indirect Cost
Name
Georgetown University
Department
Pediatrics
Type
Schools of Medicine
DUNS #
049515844
City
Washington
State
DC
Country
United States
Zip Code
20057
Wersinger, Christophe; Sidhu, Anita (2006) An inflammatory pathomechanism for Parkinson's disease? Curr Med Chem 13:591-602
Duka, Tetyana; Rusnak, Milan; Drolet, Robert E et al. (2006) Alpha-synuclein induces hyperphosphorylation of Tau in the MPTP model of parkinsonism. FASEB J 20:2302-12
Kozikowski, Alan P; Gaisina, Irina N; Petukhov, Pavel A et al. (2006) Highly potent and specific GSK-3beta inhibitors that block tau phosphorylation and decrease alpha-synuclein protein expression in a cellular model of Parkinson's disease. ChemMedChem 1:256-66
Duka, Tetyana; Sidhu, Anita (2006) The neurotoxin, MPP+, induces hyperphosphorylation of Tau, in the presence of alpha-Synuclein, in SH-SY5Y neuroblastoma cells. Neurotox Res 10:1-10
Wersinger, Christophe; Rusnak, Milan; Sidhu, Anita (2006) Modulation of the trafficking of the human serotonin transporter by human alpha-synuclein. Eur J Neurosci 24:55-64
Moussa, Charbel E-H; Tomita, York; Sidhu, Anita (2006) Dopamine D1 receptor-mediated toxicity in human SK-N-MC neuroblastoma cells. Neurochem Int 48:226-34
Wersinger, Christophe; Jeannotte, Alexis; Sidhu, Anita (2006) Attenuation of the norepinephrine transporter activity and trafficking via interactions with alpha-synuclein. Eur J Neurosci 24:3141-52
Wersinger, Christophe; Sidhu, Anita (2005) Disruption of the interaction of alpha-synuclein with microtubules enhances cell surface recruitment of the dopamine transporter. Biochemistry 44:13612-24
Chen, J; Sidhu, A (2005) The role of D1 dopamine receptors and phospho-ERK in mediating cytotoxicity. Commentary. Neurotox Res 7:179-81
Kumar, Ujendra; Chen, Jun; Sapoznikhov, Valeriy et al. (2005) Overexpression of inducible nitric oxide synthase in the kidney of the spontaneously hypertensive rat. Clin Exp Hypertens 27:17-31

Showing the most recent 10 out of 32 publications