Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
1R01NS035000-01
Application #
2274338
Study Section
AIDS and Related Research Study Section 7 (ARRG)
Project Start
1996-02-01
Project End
2001-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Mount Sinai School of Medicine
Department
Pathology
Type
Schools of Medicine
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10029
Daniel, Dianne C; Johnson, Edward M (2018) PURA, the gene encoding Pur-alpha, member of an ancient nucleic acid-binding protein family with mammalian neurological functions. Gene 643:133-143
Johnson, Edward M; Wortman, Margaret J; Dagdanova, Ayuna V et al. (2013) Polyomavirus JC in the context of immunosuppression: a series of adaptive, DNA replication-driven recombination events in the development of progressive multifocal leukoencephalopathy. Clin Dev Immunol 2013:197807
Wright, Clayton A; Nance, Jonas A; Johnson, Edward M (2013) Effects of Tat proteins and Tat mutants of different human immunodeficiency virus type 1 clades on glial JC virus early and late gene transcription. J Gen Virol 94:514-23
Darbinyan, Armine; Kaminski, Rafal; White, Martyn K et al. (2013) Polyomavirus JC infection inhibits differentiation of oligodendrocyte progenitor cells. J Neurosci Res 91:116-27
Ferenczy, Michael W; Marshall, Leslie J; Nelson, Christian D S et al. (2012) Molecular biology, epidemiology, and pathogenesis of progressive multifocal leukoencephalopathy, the JC virus-induced demyelinating disease of the human brain. Clin Microbiol Rev 25:471-506
Noch, Evan; Sariyer, Ilker Kudret; Gordon, Jennifer et al. (2012) JC virus T-antigen regulates glucose metabolic pathways in brain tumor cells. PLoS One 7:e35054
Merabova, Nana; Kaminski, Rafal; Krynska, Barbara et al. (2012) JCV agnoprotein-induced reduction in CXCL5/LIX secretion by oligodendrocytes is associated with activation of apoptotic signaling in neurons. J Cell Physiol 227:3119-27
Tavazzi, E; Ferrante, P; Khalili, K (2011) Progressive multifocal leukoencephalopathy: an unexpected complication of modern therapeutic monoclonal antibody therapies. Clin Microbiol Infect 17:1776-80
Wortman, Margaret J; Hanson, Laura K; Martinez-Sobrido, Luis et al. (2010) Regulation of PURA gene transcription by three promoters generating distinctly spliced 5-prime leaders: a novel means of fine control over tissue specificity and viral signals. BMC Mol Biol 11:81
Johnson, Edward M (2010) Structural evaluation of new human polyomaviruses provides clues to pathobiology. Trends Microbiol 18:215-23

Showing the most recent 10 out of 22 publications