Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS035291-02
Application #
2274609
Study Section
Molecular, Cellular, and Developmental Neurobiology Review Committee (MCDN)
Project Start
1995-08-01
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Alabama Birmingham
Department
Miscellaneous
Type
Schools of Arts and Sciences
DUNS #
004514360
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Li, Ping; Khatri, Alpa; Bracamontes, John et al. (2010) Site-specific fluorescence reveals distinct structural changes induced in the human rho 1 GABA receptor by inhibitory neurosteroids. Mol Pharmacol 77:539-46
Zheleznova, Nadezhda N; Sedelnikova, Anna; Weiss, David S (2009) Function and modulation of delta-containing GABA(A) receptors. Psychoneuroendocrinology 34 Suppl 1:S67-73
Zheleznova, N; Sedelnikova, A; Weiss, D S (2008) alpha1beta2delta, a silent GABAA receptor: recruitment by tracazolate and neurosteroids. Br J Pharmacol 153:1062-71
Wotring, Virginia E; Weiss, David S (2008) Charge scan reveals an extended region at the intracellular end of the GABA receptor pore that can influence ion selectivity. J Gen Physiol 131:87-97
Sedelnikova, Anna; Smith, Craig D; Zakharkin, Stanislav O et al. (2005) Mapping the rho1 GABA(C) receptor agonist binding pocket. Constructing a complete model. J Biol Chem 280:1535-42
Erkkila, Brian E; Weiss, David S; Wotring, Virginia E (2004) Picrotoxin-mediated antagonism of alpha3beta4 and alpha7 acetylcholine receptors. Neuroreport 15:1969-73
Wotring, V E; Miller, T S; Weiss, D S (2003) Mutations at the GABA receptor selectivity filter: a possible role for effective charges. J Physiol 548:527-40
Torres, Viviana I; Weiss, David S (2002) Identification of a tyrosine in the agonist binding site of the homomeric rho1 gamma-aminobutyric acid (GABA) receptor that, when mutated, produces spontaneous opening. J Biol Chem 277:43741-8
Chang, Yongchang; Ghansah, Emmanuel; Chen, Yonghui et al. (2002) Desensitization mechanism of GABA receptors revealed by single oocyte binding and receptor function. J Neurosci 22:7982-90
Ratra, Gurpreet S; Erkkila, Brian E; Weiss, David S et al. (2002) Unique insecticide specificity of human homomeric rho 1 GABA(C) receptor. Toxicol Lett 129:47-53

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