The tonotopic map of the avian basilar papilla (Callus domesticus) will be identified for two age groups (E16-17 and 2 weeks post hatch). This will be undertaken to test the hypothesis that the tonotopic map changes substantially throughout development and is not simply a """"""""scale model"""""""" of the adult. To accomplish this, individual eighth nerve neurons will be impaled. The characteristic frequency and spontaneous rate will be determined. Horseradish-peroxidase (HRP) will be iontophoretically injected into the cell and allowed to distribute throughout the cell as a cell tag. Terminals in the basilar papilla will then be identified histologically and their position expressed as a percent of the total length and width of the basilar papilla.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Academic Research Enhancement Awards (AREA) (R15)
Project #
1R15NS026000-01
Application #
3564509
Study Section
Hearing Research Study Section (HAR)
Project Start
1988-05-01
Project End
1990-04-30
Budget Start
1988-05-01
Budget End
1990-04-30
Support Year
1
Fiscal Year
1988
Total Cost
Indirect Cost
Name
University of Nebraska Lincoln
Department
Type
DUNS #
555456995
City
Lincoln
State
NE
Country
United States
Zip Code
68588
Jones, S M; Jones, T A (1995) The tonotopic map in the embryonic chicken cochlea. Hear Res 82:149-57
Jones, S M; Jones, T A (1995) Neural tuning characteristics of auditory primary afferents in the chicken embryo. Hear Res 82:139-48
Jones, T A (1992) Vestibular short latency responses to pulsed linear acceleration in unanesthetized animals. Electroencephalogr Clin Neurophysiol 82:377-86